Brain‐derived neurotrophic factor, depression, and physical activity: making the neuroplastic connection

C Phillips - Neural plasticity, 2017 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival,
growth, and maintenance of neurons in key brain circuits involved in emotional and …

Lifestyle modulators of neuroplasticity: how physical activity, mental engagement, and diet promote cognitive health during aging

C Phillips - Neural plasticity, 2017 - Wiley Online Library
The number of the elderly across the globe will approximate 2.1 billion by 2050. Juxtaposed
against this burgeoning segment of the population is evidence that nonpathological aging is …

Emotional roles of mono-aminergic neurotransmitters in major depressive disorder and anxiety disorders

Y Liu, J Zhao, W Guo - Frontiers in psychology, 2018 - frontiersin.org
A growing body of researches support a role for dysfunction of serotoninergic,
noradrenergic, and dopaminergic systems in the neurobiological processes involved in …

[HTML][HTML] PI3K/AKT signaling pathway: Molecular mechanisms and therapeutic potential in depression

N Guo, X Wang, M Xu, J Bai, H Yu, L Zhang - Pharmacological Research, 2024 - Elsevier
Depression is a serious global mental disorder. Numerous studies have found that
depression may be closely related to decreased neurogenesis, neuroinflammation …

Preserving mobility in older adults with physical frailty and sarcopenia: opportunities, challenges, and recommendations for physical activity interventions

M Billot, R Calvani, A Urtamo… - … interventions in aging, 2020 - Taylor & Francis
One of the most widely conserved hallmarks of aging is a decline in functional capabilities.
Mobility loss is particularly burdensome due to its association with negative health …

Physical exercise and neuroinflammation in major depressive disorder

ZM Ignácio, RS da Silva, ME Plissari, J Quevedo… - Molecular …, 2019 - Springer
Major depressive disorder (MDD) is a prevalent psychiatric disorder associated with varied
prognosis, chronic course, and duration of illness with reduced quality of life. One factor that …

[HTML][HTML] Genetic and epigenetic factors associated with depression: An updated overview

DS Alshaya - Saudi journal of biological sciences, 2022 - Elsevier
Depression is a complex psychiatric disturbance involving many environmental, genetic,
and epigenetic factors. Until now, genetic, and non-genetic studies are still on the way to …

Quality of life, physical activity and burnout syndrome during online learning period in Brazilian university students during the COVID-19 pandemic: a cluster analysis

DV Azzi, J Melo, AAC Neto, PM Castelo… - Psychology, health & …, 2022 - Taylor & Francis
The COVID-19 pandemic caused several changes in the teaching-learning process, as it
abruptly replaced the conventional classes into online classes despite social distancing …

Modulation of neurotrophic factors in the treatment of dementia, stroke and TBI: Effects of Cerebrolysin

K Rejdak, H Sienkiewicz‐Jarosz… - Medicinal Research …, 2023 - Wiley Online Library
Neurotrophic factors (NTFs) are involved in the pathophysiology of neurological disorders
such as dementia, stroke and traumatic brain injury (TBI), and constitute molecular targets of …

[HTML][HTML] Therapeutic interventions to mitigate mitochondrial dysfunction and oxidative stress–induced damage in patients with bipolar disorder

S Madireddy, S Madireddy - International journal of molecular sciences, 2022 - mdpi.com
Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …