Benefits of exercise training on cerebrovascular and cognitive function in ageing

ES Bliss, RHX Wong, PRC Howe… - Journal of Cerebral …, 2021 - journals.sagepub.com
Derangements in cerebrovascular structure and function can impair cognitive performance
throughout ageing and in cardiometabolic disease states, thus increasing dementia risk …

The utility of cerebral blood flow as a biomarker of preclinical Alzheimer's disease

CC Hays, ZZ Zlatar, CE Wierenga - Cellular and molecular neurobiology, 2016 - Springer
There is accumulating evidence suggesting that changes in brain perfusion are present long
before the clinical symptoms of Alzheimer's disease (AD), perhaps even before amyloid-β …

Detection of subjects and brain regions related to Alzheimer's disease using 3D MRI scans based on eigenbrain and machine learning

Y Zhang, Z Dong, P Phillips, S Wang, G Ji… - Frontiers in …, 2015 - frontiersin.org
Purpose: Early diagnosis or detection of Alzheimer's disease (AD) from the normal elder
control (NC) is very important. However, the computer-aided diagnosis (CAD) was not …

[HTML][HTML] Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimer's disease

N Zhang, ML Gordon, TE Goldberg - Neuroscience & Biobehavioral …, 2017 - Elsevier
Arterial spin labeling (ASL) magnetic resonance imaging uses arterial blood water as an
endogenous tracer to measure cerebral blood flow (CBF). In this review, based on ASL …

Cerebral blood flow measured by arterial spin labeling MRI as a preclinical marker of Alzheimer's disease

CE Wierenga, CC Hays… - Journal of Alzheimer's …, 2014 - content.iospress.com
There is growing recognition that cerebral hypoperfusion is related to the pathogenesis of
Alzheimer's disease (AD), implicating the measurement of cerebral blood flow (CBF) as a …

Cerebral blood flow measurements in adults: a review on the effects of dietary factors and exercise

PJ Joris, RP Mensink, TC Adam, TT Liu - Nutrients, 2018 - mdpi.com
Improving cerebrovascular function may be a key mechanism whereby a healthy lifestyle, of
which a healthy diet combined with increased physical activity levels is a cornerstone …

Reduced regional cerebral blood flow relates to poorer cognition in older adults with type 2 diabetes

KJ Bangen, ML Werhane, AJ Weigand… - Frontiers in aging …, 2018 - frontiersin.org
Type 2 diabetes mellitus (T2DM) increases risk for dementia, including Alzheimer's disease
(AD). Many previous studies of brain changes underlying cognitive impairment in T2DM …

Separating vascular and neuronal effects of age on fMRI BOLD signals

KA Tsvetanov, RNA Henson… - … Transactions of the …, 2021 - royalsocietypublishing.org
Accurate identification of brain function is necessary to understand the neurobiology of
cognitive ageing, and thereby promote well-being across the lifespan. A common tool used …

Variability of physiological brain perfusion in healthy subjects–A systematic review of modifiers. Considerations for multi-center ASL studies

P Clement, HJ Mutsaerts, L Václavů… - Journal of Cerebral …, 2018 - journals.sagepub.com
Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …

Cerebral blood flow and cognitive functioning in a community-based, multi-ethnic cohort: the SABRE study

AE Leeuwis, LA Smith, A Melbourne… - Frontiers in aging …, 2018 - frontiersin.org
Introduction: Lower cerebral blood flow (CBF) is associated with cardiovascular disease and
vascular risk factors, and is increasingly acknowledged as an important contributor to …