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Antiretroviral therapy and management of HIV infection
Antiretroviral therapy of HIV infection has changed a uniformly fatal into a potentially chronic
disease. There are now 17 drugs in common use for HIV treatment. Patients who can access …
disease. There are now 17 drugs in common use for HIV treatment. Patients who can access …
[HTML][HTML] Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies
When To Start Consortium - The Lancet, 2009 - Elsevier
BACKGROUND: The CD4 cell count at which combination antiretroviral therapy should be
started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of …
started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of …
Effect of early versus deferred antiretroviral therapy for HIV on survival
Background The optimal time for the initiation of antiretroviral therapy for asymptomatic
patients with human immunodeficiency virus (HIV) infection is uncertain. Methods We …
patients with human immunodeficiency virus (HIV) infection is uncertain. Methods We …
Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society–USA panel
Context The availability of new antiretroviral drugs and formulations, including drugs in new
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …
classes, and recent data on treatment choices for antiretroviral-naive and-experienced …
Incomplete Peripheral CD4+ Cell Count Restoration in HIV-Infected Patients Receiving Long-Term Antiretroviral Treatment
Background. Although antiretroviral therapy has the ability to fully restore a normal CD4+
cell count (> 500 cells/mm3) in most patients, it is not yet clear whether all patients can …
cell count (> 500 cells/mm3) in most patients, it is not yet clear whether all patients can …
Enhanced T cell recovery in HIV-1–infected adults through IL-7 treatment
Y Levy, C Lacabaratz, L Weiss, JP Viard… - The Journal of clinical …, 2009 - jci.org
HIV infection results in CD4+ T cell deficiency, but efficient combination antiretroviral therapy
(c-ART) restores T cells and decreases morbidity and mortality. However, immune …
(c-ART) restores T cells and decreases morbidity and mortality. However, immune …
Current status and challenges of antiretroviral research and therapy
JA Esté, T Cihlar - Antiviral research, 2010 - Elsevier
Twenty-five years after the discovery of the therapeutic activity of azidothymidine (AZT), the
first antiretroviral drug used in the clinic, infection with the human immunodeficiency virus …
first antiretroviral drug used in the clinic, infection with the human immunodeficiency virus …
Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384
Background. Initiation of combination antiretroviral therapy (ART) results in higher total CD4
cell counts, a surrogate for immune reconstitution. Whether the baseline CD4 cell count …
cell counts, a surrogate for immune reconstitution. Whether the baseline CD4 cell count …
The future role of CD4 cell count for monitoring antiretroviral therapy
For more than two decades, CD4 cell count measurements have been central to
understanding HIV disease progression, making important clinical decisions, and monitoring …
understanding HIV disease progression, making important clinical decisions, and monitoring …
Long-term immunologic response to antiretroviral therapy in low-income countries: a collaborative analysis of prospective studies
Background: Few data are available on the long-term immunologic response to antiretroviral
therapy (ART) in resource-limited settings, where ART is being rapidly scaled up using a …
therapy (ART) in resource-limited settings, where ART is being rapidly scaled up using a …