[HTML][HTML] Neurotoxicity and underlying mechanisms of endogenous neurotoxins

Y Cao, B Li, N Ismail, K Smith, T Li, R Dai… - International journal of …, 2021 - mdpi.com
Endogenous and exogenous neurotoxins are important factors leading to
neurodegenerative diseases. In the 1980s, the discovery that 1-methyl-4-phenyl-1, 2, 3, 6 …

Novel pharmacotherapies in Parkinson's disease

Y Tizabi, B Getachew, M Aschner - Neurotoxicity Research, 2021 - Springer
Abstract Parkinson's disease (PD), an age-related progressive neurodegenerative condition,
is associated with loss of dopaminergic neurons in the substantia nigra pars compacta …

A secret that underlies Parkinson's disease: The damaging cycle

F Sun, Y Deng, X Han, Q Liu, P Zhang… - Neurochemistry …, 2019 - Elsevier
Parkinson's disease (PD) is a movement disorder, and its common characteristics include
the loss of dopaminergic neurons and the accumulation of a special type of cytoplasmic …

Neuroprotective effect and mechanism of baicalin on Parkinson's disease model induced by 6-OHDA

L Tu, ZY Wu, XL Yang, Q Zhang, R Gu… - Neuropsychiatric …, 2019 - Taylor & Francis
Objective This research was aimed to investigate the effects of baicalin on 6-
hydroxydopamine (6-OHDA)-induced rat model of Parkinson's disease (PD) and the main …

The mechanism of action of salsolinol in brain: implications in Parkinson's disease

SM Voon, KY Ng, SM Chye, APK Ling… - CNS & Neurological …, 2020 - benthamdirect.com
1-Methyl-1, 2, 3, 4-tetrahydroisoquinoline-6, 7-diol, commonly known as salsolinol, is a
compound derived from dopamine. It was first discovered in 1973 and has gained attention …

In vitro neurotoxicity of salsolinol is attenuated by the presynaptic protein α-synuclein

P do Carmo-Gonçalves, E Coelho-Cerqueira… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Background Salsolinol (SALSO), a product from the reaction of dopamine (DA) with
acetaldehyde, is found increased in dopaminergic neurons of Parkinson's disease (PD) …

Enteric Neurotoxicity and Salsolinol

M Kurnik-Łucka, K Gil - Handbook of Neurotoxicity, 2023 - Springer
The perception of the enteric nervous system has immensely changed since the first
detection of salsolinol in the urine of Parkinsonian patients treated with L-DOPA medication …

Enteric neurotoxicity and salsolinol

M Kurnik-Łucka, K Gil - Handbook of Neurotoxicity, 2021 - Springer
The perception of the enteric nervous system has immensely changed since the first
detection of salsolinol in the urine of Parkinsonian patients treated with L-DOPA medication …

Neurotoxicity of salsolinol through apoptosis induction and oxidative stress in BV2 microglial cells

JN Oo, RY Koh, YQ Leong, SM Chye… - Current Topics in …, 2023 - research.monash.edu
Salsolinol (SAL) is an endogenous neurotoxin identified as a potential aetiological factor in
Parkinson's disease (PD). Its neurotoxicity through apoptosis induction and oxidative stress …