Mechanisms and regulation of defensins in host defense

J Fu, X Zong, M **, J Min, F Wang… - Signal Transduction and …, 2023 - nature.com
As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Dietary polyphenol impact on gut health and microbiota

MLY Wan, VA Co, H El-Nezami - Critical reviews in food science …, 2021 - Taylor & Francis
Polyphenols are naturally occurring compounds in plants and they are the most abundant
antioxidants in the human diet. Due to their considerable structural diversity, this largely …

[HTML][HTML] Polyphenols in oral health: homeostasis maintenance, disease prevention, and therapeutic applications

Y Guo, Z Li, F Chen, Y Chai - Nutrients, 2023 - mdpi.com
Polyphenols, a class of bioactive compounds with phenolic structures, are abundant in
human diets. They have gained attention in biomedical fields due to their beneficial …

Tea polyphenols inhibit the growth and virulence properties of Fusobacterium nucleatum

A Ben Lagha, B Haas, D Grenier - Scientific Reports, 2017 - nature.com
Fusobacterium nucleatum plays a key role in creating the pathogenic subgingival biofilm
that initiates destructive periodontitis. It is also a common resident of the human …

Host defense peptides in nutrition and diseases: a contributor of immunology modulation

X Dou, D Yan, S Liu, N Gao, Z Ma, Z Shi… - Journal of Agricultural …, 2023 - ACS Publications
Host defense peptides (HDPs) are primary components of the innate immune system with
diverse biological functions, such as antibacterial ability and immunomodulatory function …

Green tea catechins potentiate the effect of antibiotics and modulate adherence and gene expression in Porphyromonas gingivalis

J Fournier-Larente, MP Morin, D Grenier - Archives of Oral Biology, 2016 - Elsevier
Objectives A number of studies have brought evidence that green tea catechins may
contribute to periodontal health. The objective of this study was to investigate the ability of a …

Flavonoids exert multiple periodontic benefits including anti-inflammatory, periodontal ligament-supporting, and alveolar bone-preserving effects

B Fernández-Rojas, G Gutiérrez-Venegas - Life sciences, 2018 - Elsevier
Flavonoids are plant-derived polyphenolic compounds claimed to help alleviate a variety of
conditions, including diabetes, infectious endocarditis, and cancer. They have attracted …

Human β-defensins and their synthetic analogs: Natural defenders and prospective new drugs of oral health

M Chen, Z Hu, J Shi, Z **e - Life sciences, 2024 - Elsevier
As a family of cationic host defense peptides, human β-defensins (HBDs) are ubiquitous in
the oral cavity and are mainly synthesized primarily by epithelial cells, serving as the primary …

Black tea extract and its theaflavin derivatives inhibit the growth of periodontopathogens and modulate interleukin-8 and β-defensin secretion in oral epithelial cells

TB Lombardo Bedran, MP Morin… - PLoS …, 2015 - journals.plos.org
Over the years, several studies have brought evidence suggesting that tea polyphenols,
mostly from green tea, may have oral health benefits. Since few data are available …

[HTML][HTML] Effects of Green Tea Extract Epigallocatechin-3-Gallate on oral diseases: a narrative review

Y Li, L Cheng, M Li - Pathogens, 2024 - mdpi.com
Objectives: Oral diseases are among the most prevalent diseases globally. Accumulating
new evidence suggests considerable benefits of epigallocatechin-3-gallate (EGCG) for oral …