Calcium-activated non-specific cation (CAN) channels are found in a broad range of cells,
including cardiac cells, secretory cells, and neurons. Single channel recordings indicate that …

-Z+ examples of the reverse, Ca-induced inhibition of ion channels, have recently been
found. Ca2+-dependent channels help to shape the action potentials of excitable cells as …

A network of oscillatory bursting neurons with excitatory coupling is hypothesized to define
the primary kernel for respiratory rhythm generation in the pre-Bötzinger complex (pre …

Pacemaker neurons have been described in most neural networks. However, whether such
neurons are essential for generating an activity pattern in a given preparation remains …

Neurons of the cerebellar nuclei fire spontaneous action potentials both in vitro, with
synaptic transmission blocked, and in vivo, in resting animals, despite ongoing inhibition …

Subiculum is the primary output area of the hippocampus and serves as a key relay center in
the process of memory formation and retrieval. A majority of subicular pyramidal neurons …

Approximately 28% of dorsal horn neurons (DHNs) in lamina V of the rat spinal cord
generate voltage-dependent plateau potentials underlying accelerating discharges and …

The dorsal raphe (DR) receives a prominent dopamine (DA) input that has been suggested
to play a key role in the regulation of central serotoninergic transmission. DA is known to …

Abstract TRPM4 is a Ca 2+-activated nonselective cation channel. The channel is activated
by an increase of intracellular Ca 2+ and is regulated by several factors including …

Calcium-activated nonselective cationic currents have been known for 30 years, but their
physiological implications have remained unresolved until the recent cloning of the TRPM4 …