Aspergillus flavus is saprophytic soil fungus that infects and contaminates preharvest and
postharvest seed crops with the carcinogenic secondary metabolite aflatoxin. The fungus is …

Lichens, which are defined by a core symbiosis between a mycobiont (fungal partner) and a
photobiont (photoautotrophic partner), are in fact complex assemblages of microorganisms …

Quinones are widely distributed in nature and exhibit diverse biological or pharmacological
activities; however, their biosynthetic machineries are largely unknown. The …

Background Secondary metabolite production, a hallmark of filamentous fungi, is an
expanding area of research for the Aspergilli. These compounds are potent chemicals …

The initial focus of recombinant protein production by filamentous fungi related to exploiting
the extraordinary extracellular enzyme synthesis and secretion machinery of industrial …

The iterative type I polyketide synthases (IPKSs) are central to the biosynthesis of an
enormously diverse array of natural products in fungi. These natural products, known as …

To reduce the secondary metabolite background in Aspergillus nidulans and minimize the
rediscovery of compounds and pathway intermediates, we created a “genetic dereplication” …

Covering: 2005 to 2011 This review studies the impact of whole genome sequencing on
Aspergillus secondary metabolite research. There has been a proliferation of many new …

Biosynthetic pathways of secondary metabolites from fungi are currently subject to an
intense effort to elucidate the genetic basis for these compounds due to their large potential …

Fungal secondary metabolites (SMs) are an important source of medically valuable
compounds. Genome projects have revealed that fungi have many SM biosynthetic gene …