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[HTML][HTML] Kinetic models in industrial biotechnology–improving cell factory performance
An increasing number of industrial bioprocesses capitalize on living cells by using them as
cell factories that convert sugars into chemicals. These processes range from the production …
cell factories that convert sugars into chemicals. These processes range from the production …
Constructing kinetic models of metabolism at genome‐scales: a review
S Srinivasan, WR Cluett, R Mahadevan - Biotechnology journal, 2015 - Wiley Online Library
Constraint‐based modeling of biological networks (metabolism, transcription and signal
transduction), although used successfully in many applications, suffer from specific …
transduction), although used successfully in many applications, suffer from specific …
Assessment of prediction uncertainty quantification methods in systems biology
Biological processes are often modelled using ordinary differential equations. The unknown
parameters of these models are estimated by optimizing the fit of model simulation and …
parameters of these models are estimated by optimizing the fit of model simulation and …
Designing biological systems: systems engineering meets synthetic biology
Synthetic Biology offers qualitatively new perspectives on the benefits of industrially
harnessed biological processes. The ability to modify and reprogramme natural biology …
harnessed biological processes. The ability to modify and reprogramme natural biology …
Parameter estimation in large-scale systems biology models: a parallel and self-adaptive cooperative strategy
Background The development of large-scale kinetic models is one of the current key issues
in computational systems biology and bioinformatics. Here we consider the problem of …
in computational systems biology and bioinformatics. Here we consider the problem of …