Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia

S Peixoto da Silva, JMO Santos… - Journal of cachexia …, 2020 - Wiley Online Library
Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic …

Understanding cachexia as a cancer metabolism syndrome

PE Porporato - Oncogenesis, 2016 - nature.com
Metabolic reprogramming occurs in tumors to foster cancer cell proliferation, survival and
metastasis, but as well at a systemic level affecting the whole organism, eventually leading …

Inter-tissue communication in cancer cachexia

JM Argilés, B Stemmler, FJ López-Soriano… - Nature Reviews …, 2019 - nature.com
Cachexia is a systemic condition that occurs during many neoplastic diseases, such as
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …

Molecular mechanisms of muscle fatigue

D Constantin-Teodosiu, D Constantin - International journal of molecular …, 2021 - mdpi.com
Muscle fatigue (MF) declines the capacity of muscles to complete a task over time at a
constant load. MF is usually short-lasting, reversible, and is experienced as a feeling of …

Skeletal muscle wasting and renewal: a pivotal role of myokine IL-6

JE Belizário, CC Fontes-Oliveira, JP Borges… - Springerplus, 2016 - Springer
Adult skeletal tissue is composed of heterogeneous population of cells that constantly self-
renew by means of a controlled process of activation and proliferation of tissue-resident …

[HTML][HTML] Out of control: the role of the ubiquitin proteasome system in skeletal muscle during inflammation

S Haberecht-Müller, E Krüger, J Fielitz - Biomolecules, 2021 - mdpi.com
The majority of critically ill intensive care unit (ICU) patients with severe sepsis develop ICU-
acquired weakness (ICUAW) characterized by loss of muscle mass, reduction in myofiber …

[HTML][HTML] The involvement of the ubiquitin proteasome system in human skeletal muscle remodelling and atrophy

AJ Murton, D Constantin, PL Greenhaff - Biochimica et Biophysica Acta …, 2008 - Elsevier
Skeletal muscle exhibits great plasticity in response to altered activity levels, ultimately
resulting in tissue remodelling and substantial changes in mass. Animal research would …

Contribution of intramuscular connective tissue and its structural components on meat tenderness-revisited: a review

BC Roy, HL Bruce - Critical Reviews in Food Science and Nutrition, 2024 - Taylor & Francis
The tenderness of meat influences consumers' perceptions of its quality. Meat tenderness is
a key quality characteristic that influences consumer satisfaction, repeat purchases, and …

[HTML][HTML] Zinc at the crossroads of exercise and proteostasis

JD Hernández-Camacho, C Vicente-García… - Redox biology, 2020 - Elsevier
Zinc is an essential element for all forms of life, and one in every ten human proteins is a
zinc protein. Zinc has catalytic, structural and signalling functions and its correct …

[HTML][HTML] Invited review: Muscle protein breakdown and its assessment in periparturient dairy cows

H Sadri, MH Ghaffari, H Sauerwein - Journal of dairy science, 2023 - Elsevier
Mobilization of body reserves including fat, protein, and glycogen is necessary to overcome
phases of negative nutrient balance typical for high-yielding dairy cows during the …