Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae

SA Henry, SD Kohlwein, GM Carman - Genetics, 2012 - academic.oup.com
Due to its genetic tractability and increasing wealth of accessible data, the yeast
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …

Metabolism and functions of phosphatidylserine

JE Vance, R Steenbergen - Progress in lipid research, 2005 - Elsevier
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is
synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and …

Membrane phosphatidylserine regulates surface charge and protein localization

T Yeung, GE Gilbert, J Shi, J Silvius, A Kapus… - Science, 2008 - science.org
Electrostatic interactions with negatively charged membranes contribute to the subcellular
targeting of proteins with polybasic clusters or cationic domains. Although the anionic …

The saccharomyces cerevisiae lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme*♦

GS Han, WI Wu, GM Carman - Journal of Biological Chemistry, 2006 - ASBMB
Mg 2+-dependent phosphatidate (PA) phosphatase (3-sn-phosphatidate phosphohydrolase,
EC 3.1. 3.4) catalyzes the dephosphorylation of PA to yield diacylglycerol and P i. In this …

The plasma membrane of Saccharomyces cerevisiae: structure, function, and biogenesis

ME Van Der Rest, AH Kamminga, A Nakano… - Microbiological …, 1995 - Am Soc Microbiol
The composition of phospholipids, sphingolipids, and sterols in the plasma membrane has a
strong influence on the activity of the proteins associated or embedded in the lipid bilayer …

Distribution, dynamics and functional roles of phosphatidylserine within the cell

JG Kay, GD Fairn - Cell Communication and Signaling, 2019 - Springer
Phosphatidylserine (PtdSer), an essential constituent of eukaryotic membranes, is the most
abundant anionic phospholipid in the eukaryotic cell accounting for up to 10% of the total …

Regulation of Phospholipid Synthesis in the Yeast Saccharomyces cerevisiae

GM Carman, GS Han - Annual review of biochemistry, 2011 - annualreviews.org
The yeast Saccharomyces cerevisiae, with its full complement of organelles, synthesizes
membrane phospholipids by pathways that are generally common to those found in higher …

Isolation and characterization of OLE1, a gene affecting fatty acid desaturation from Saccharomyces cerevisiae

JE Stukey, VM McDonough, CE Martin - Journal of Biological Chemistry, 1989 - ASBMB
The unsaturated fatty acid (ufa) requiring ole1 mutant of Saccharomyces cerevisiae appears
to produce a defective Δ-9 fatty acid desaturase. This enzyme catalyzes double bond …

Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes

GM Carman, SA Henry - Progress in lipid research, 1999 - Elsevier
In this article, we will review recent progress in elucidating the mechanisms that regulate
phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and discuss advances in …

[HTML][HTML] Checks and balances in membrane phospholipid class and acyl chain homeostasis, the yeast perspective

AIPM de Kroon, PJ Rijken, CH De Smet - Progress in lipid research, 2013 - Elsevier
Glycerophospholipids are the most abundant membrane lipid constituents in most
eukaryotic cells. As a consequence, phospholipid class and acyl chain homeostasis are …