On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

A Galano, DX Tan, RJ Reiter - Journal of pineal research, 2013 - Wiley Online Library
The reactions of N 1‐acetyl‐N 2‐formyl‐5‐methoxykynuramine (AFMK) and N 1‐acetyl‐5‐
methoxykynuramine (AMK) with• OH,• OOH, and• OOCC l3 radicals have been studied using …

A computational methodology for accurate predictions of rate constants in solution: Application to the assessment of primary antioxidant activity

A Galano, JR Alvarez‐Idaboy - Journal of computational …, 2013 - Wiley Online Library
The accurate prediction of rate constants for chemical reactions in solution, using
computational methods, is a challenging task. In this work, a computational protocol …

Theoretical and experimental studies of the antioxidant and antinitrosant activity of syringic acid

QV Vo, MV Bay, PC Nam, DT Quang… - The Journal of …, 2020 - ACS Publications
Syringic acid (SA) is a natural phenolic acid found in vegetables, fruits, and other plant-
based foods. A range of biological activities were proposed for this compound including …

A physicochemical examination of the free radical scavenging activity of Trolox: mechanism, kinetics and influence of the environment

ME Alberto, N Russo, A Grand, A Galano - Physical chemistry chemical …, 2013 - pubs.rsc.org
The free radical scavenging activity of Trolox was studied for aqueous and lipid
environments using the Density Functional Theory. Several reaction mechanisms and free …

Antioxidant Activity of trans-Resveratrol toward Hydroxyl and Hydroperoxyl Radicals: A Quantum Chemical and Computational Kinetics Study

C Iuga, JR Alvarez-Idaboy, N Russo - The Journal of organic …, 2012 - ACS Publications
In this work, we have carried out a systematic study of the antioxidant activity of trans-
resveratrol toward hydroxyl (• OH) and hydroperoxyl (• OOH) radicals in aqueous simulated …

Radical scavenging ability of gallic acid toward OH and OOH radicals. Reaction mechanism and rate constants from the density functional theory

T Marino, A Galano, N Russo - The Journal of Physical Chemistry …, 2014 - ACS Publications
Gallic acid is a ubiquitous compound, widely distributed in the vegetal kingdom and
frequently found in the human diet. In the present work, its primary antioxidant activity has …

Is caffeine a good scavenger of oxygenated free radicals?

JR León-Carmona, A Galano - The journal of physical chemistry B, 2011 - ACS Publications
The reactions of caffeine (CAF) with different reactive oxygen species (ROS) have been
studied using density functional theory. Five mechanisms of reaction have been considered …

On the direct scavenging activity of melatonin towards hydroxyl and a series of peroxyl radicals

A Galano - Physical Chemistry Chemical Physics, 2011 - pubs.rsc.org
The reactions of melatonin (MLT) with hydroxyl and several peroxyl radicals have been
studied using the Density Functional Theory, specifically the M05-2X functional. Five …

Glutathione: mechanism and kinetics of its non-enzymatic defense action against free radicals

A Galano, JR Alvarez-Idaboy - Rsc Advances, 2011 - pubs.rsc.org
Glutathione, which is the most abundant cytosolic thiol, plays important roles in the non-
enzymatic antioxidant defence system. Its free radical scavenging activity towards radicals of …

Ellagic acid: an unusually versatile protector against oxidative stress

A Galano, M Francisco Marquez… - Chemical research in …, 2014 - ACS Publications
Several aspects related to the antioxidant activity of ellagic acid were investigated using the
density functional theory. It was found that this compound is unusually versatile for protecting …