Current perspectives on the use of intravenous recombinant tissue plasminogen activator (tPA) for treatment of acute ischemic stroke
In 1995, the NINDS (National Institute of Neurological Disorders and Stroke) tPA (tissue
plasminogen activator) Stroke Study Group published the results of a large multicenter …
plasminogen activator) Stroke Study Group published the results of a large multicenter …
Imaging-guided acute ischemic stroke therapy: from “time is brain” to “physiology is brain”
RG Gonzalez - American Journal of Neuroradiology, 2006 - Am Soc Neuroradiology
The number of potential patients who are actually treated for acute ischemic stroke is
disappointingly low, and effective treatments are making a minor impact on this major public …
disappointingly low, and effective treatments are making a minor impact on this major public …
Eligibility for intravenous recombinant tissue-type plasminogen activator within a population: the effect of the European Cooperative Acute Stroke Study (ECASS) III …
F de los Ríos la Rosa, J Khoury, BM Kissela… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—The publication of the European Cooperative Acute Stroke
Study (ECASS III) expanded the treatment time to thrombolysis for acute ischemic stroke …
Study (ECASS III) expanded the treatment time to thrombolysis for acute ischemic stroke …
Outcome of stroke with mild or rapidly improving symptoms
K Nedeltchev, B Schwegler, T Haefeli, C Brekenfeld… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Acute ischemic stroke with mild or rapidly improving symptoms
is expected to result in good functional outcome, whether treated or not. Therefore …
is expected to result in good functional outcome, whether treated or not. Therefore …
Poor outcomes in patients who do not receive intravenous tissue plasminogen activator because of mild or improving ischemic stroke
Background and Purpose—Some patients with mild or improving ischemic stroke symptoms
do not receive intravenous tissue plasminogen activator (tPA) because they look “too good …
do not receive intravenous tissue plasminogen activator (tPA) because they look “too good …
Outcome of patients with occlusions of the internal carotid artery or the main stem of the middle cerebral artery with NIHSS score of less than 5: comparison between …
Background and purpose The use of thrombolysis in patients with minor neurological deficits
and large vessel occlusion is controversial. Methods We compared the outcome of patients …
and large vessel occlusion is controversial. Methods We compared the outcome of patients …
Time and diffusion lesion size in major anterior circulation ischemic strokes
R Hakimelahi, BA Vachha, WA Copen, GDE Papini… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Major anterior circulation ischemic strokes caused by occlusion
of the distal internal carotid artery or proximal middle cerebral artery or both account for …
of the distal internal carotid artery or proximal middle cerebral artery or both account for …
Existence of the Diffusion-Perfusion Mismatch within 24 Hours after Onset of Acute Stroke: Dependence on Proximal Arterial Occlusion1
WA Copen, L Rezai Gharai, ER Barak, LH Schwamm… - Radiology, 2009 - pubs.rsna.org
Purpose: To assess the existence of a mismatch between lesions on diffusion-weighted
(DW) and perfusion-weighted (PW) magnetic resonance (MR) images obtained within 24 …
(DW) and perfusion-weighted (PW) magnetic resonance (MR) images obtained within 24 …
Can a media campaign change health service use in a population with stroke symptoms? Examination of the first Irish stroke awareness campaign
Background Mass media campaigns for stroke awareness encourage the public to
recognise stroke symptoms and respond to stroke in a timely manner. However, there is little …
recognise stroke symptoms and respond to stroke in a timely manner. However, there is little …
The exact science of stroke thrombolysis and the quiet art of patient selection
JS Balami, G Hadley, BA Sutherland, H Karbalai… - Brain, 2013 - academic.oup.com
The science of metric-based patient stratification for intravenous thrombolysis, revolutionized
by the landmark National Institute of Neurological Disorders and Stroke trial, has …
by the landmark National Institute of Neurological Disorders and Stroke trial, has …