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The cell biology of ferroptosis
Ferroptosis is a non-apoptotic cell death mechanism characterized by iron-dependent
membrane lipid peroxidation. Here, we review what is known about the cellular mechanisms …
membrane lipid peroxidation. Here, we review what is known about the cellular mechanisms …
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies
Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - Signal transduction and …, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …
Targeting ferroptosis opens new avenues for the development of novel therapeutics
S Sun, J Shen, J Jiang, F Wang, J Min - Signal transduction and …, 2023 - nature.com
Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
Enhancing the intracellular labile iron pool (LIP) represents a powerful, yet untapped
strategy for driving ferroptotic death of cancer cells. Here, we show that NRF2 maintains iron …
strategy for driving ferroptotic death of cancer cells. Here, we show that NRF2 maintains iron …
Role of pyroptosis in inflammation and cancer
X Wei, F **e, X Zhou, Y Wu, H Yan, T Liu… - Cellular & molecular …, 2022 - nature.com
Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …
physiology and pathology in living systems, making significant contributions to life science …
The multifaceted role of ferroptosis in liver disease
Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by
excessive lipid peroxidation and associated with a plethora of pathological conditions in the …
excessive lipid peroxidation and associated with a plethora of pathological conditions in the …
Ferroptosis in cancer and cancer immunotherapy
The hallmark of tumorigenesis is the successful circumvention of cell death regulation for
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …
achieving unlimited replication and immortality. Ferroptosis is a newly identified type of cell …
Ceria‐based therapeutic antioxidants for biomedical applications
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …
Reactive oxygen species in cancer: Current findings and future directions
H Nakamura, K Takada - Cancer science, 2021 - Wiley Online Library
Reactive oxygen species (ROS), a class of highly bioactive molecules, have been widely
studied in various types of cancers. ROS are considered to be normal byproducts of …
studied in various types of cancers. ROS are considered to be normal byproducts of …