Asymmetric catalysis plays a key role in modern synthetic organic chemistry, with synthetic
catalysts and enzymes being the two available options. During the latter part of the last …

Glycosylation reactions mainly catalyzed by glycosyltransferases (Gts) occur almost
everywhere in the biosphere, and always play crucial roles in vital processes. In order to …

Natural products and their derivatives play an important role in modern healthcare as
frontline treatments for many diseases and as inspiration for chemically synthesized …

Glycosylation is a chemical transformation that is centrally important in all glycoscience and
related technologies. Catalysts offering good control over reactivity and selectivity in …

Covering: up to the end of May 2011 Glyco (randomization/diversification) is a term that
encompasses strategies to diversify a core drug scaffold via enzymatic glycosylation to …

Biocatalytic conversions can involve one enzyme that carries out one specific reaction at a
time, or multiple enzymes that carry out a series of conversions to yield a desired product …

Glycosylation of small molecules like specialized (secondary) metabolites has a profound
impact on their solubility, stability or bioactivity, making glycosides attractive compounds as …

Abstract Background The glucosyltransferase UGT76G1 from Stevia rebaudiana is a
chameleon enzyme in the targeted biosynthesis of the next-generation premium stevia …

A large number of antibiotics are glycosides. In numerous cases the glycosidic residues are
crucial to their activity; sometimes, glycosylation only improves their pharmacokinetic …

Glycosyltransferases (GTs) are ubiquitous in nature and are required for the transfer of
sugars to a variety of important biomolecules. This essential enzyme family has been a focus …