▪ Abstract The conversion of physical signals, such as contractile forces or external
mechanical perturbations, into chemical signaling events is a fundamental cellular process …

Cell movement is a complex phenomenon primarily driven by the actin network beneath the
cell membrane, and can be divided into three general components: protrusion of the leading …

The mechanism by which epithelial, endothelial and other strongly cell-cell adhesive cells
migrate collectively as continuous sheets is not clear, even though this process is crucial for …

Formins are large multidomain proteins required for assembly of actin cables that contribute
to the polarity and division of animal and fungal cells. F ormin h omology-1 (FH1) domains …

We report hybrid lattice Boltzmann (HLB) simulations of the hydrodynamics of an active
nematic liquid crystal sandwiched between confining walls with various anchoring …

A wide variety of soluble signaling substances utilize the cyclic AMP-dependent protein
kinase (PKA) pathway to regulate cellular behaviors including intermediary metabolism, ion …

The actin cytoskeleton is one of the major structural components of the cell. It often
undergoes rapid reorganization and plays crucial roles in a number of dynamic cellular …

Background: Metastasis is the primary cause of death in most human cancers, and
understanding the molecular mechanisms underpinning this multistep process is …

Subversion of host cell actin microfilaments is the hallmark of enterohaemorrhagic (EHEC)
and enteropathogenic (EPEC) Escherichia coli infections. Both pathogens translocate the …

Vasodilator‐stimulated phosphoprotein (VASP) is a key regulator of dynamic actin structures
like filopodia and lamellipodia, but its precise function in their formation is controversial …