Toxins and pharmacologically active compounds from species of the family Bufonidae (Amphibia, Anura)

C Rodríguez, L Rollins-Smith, R Ibáñez… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Among amphibians, 15 of the 47 species reported to be
used in traditional medicines belong to the family Bufonidae, which demonstrates their …

Metabolomic approaches for the determination of metabolites from pathogenic microorganisms: A review

AB Oyedeji, E Green, JA Adebiyi, OM Ogundele… - Food Research …, 2021 - Elsevier
Metabolomics is a high precision analytical approach to obtaining detailed information of
varieties of metabolites produced in biological systems, including foods. This study reviews …

Application of feature-based molecular networking and MassQL for the MS/MS fragmentation study of depsipeptides

DM Selegato, AC Zanatta, AC Pilon… - Frontiers in Molecular …, 2023 - frontiersin.org
The Feature-based Molecular Networking (FBMN) is a well-known approach for map**
and identifying structures and analogues. However, in the absence of prior knowledge about …

Advances in linking polyketides and non-ribosomal peptides to their biosynthetic gene clusters in Fusarium

MR Nielsen, TE Sondergaard, H Giese, JL Sørensen - Current Genetics, 2019 - Springer
The eukaryotic ascomycete genus Fusarium comprises many species capable of producing
secondary metabolites important for agriculture, health, and biotechnology. Filamentous …

Plant metabolomics using NMR spectroscopy

DM Selegato, AC Pilon, F Carnevale Neto - NMR-Based Metabolomics …, 2019 - Springer
The major goal in plant metabolomics is to study complex extracts for the purposes of
metabolic exploration and natural products discovery. To achieve this goal, plant …

[HTML][HTML] Update: Biological and Chemical Aspects of Senna spectabilis

DM Selegato, AF Monteiro, NC Vieira… - Journal of the Brazilian …, 2017 - SciELO Brasil
Senna spectabilis (syn Cassia spectabilis) is one of the most important species within the
Fabaceae family, natively found in Central and South America, as well as parts of Asia and …

Artificial Intelligence and Discovery of Microbial Natural Products

R Hamdy, AM Altaie, EM El-Labbad… - Drug Discovery and …, 2023 - Springer
Natural products (NPs) have a variety of potential medicinal applications as drug or lead
molecules for drug development. NPs are subset of small chemical molecules known as …

Improvement of bioactive metabolite production in microbial cultures—A systems approach by OSMAC and deconvolution‐based 1HNMR quantification

DM Selegato, RT Freire, AC Pilon… - Magnetic …, 2019 - Wiley Online Library
Traditionally, the screening of metabolites in microbial matrices is performed by
monocultures. Nonetheless, the absence of biotic and abiotic interactions generally …

Drug development projects guided by ethnobotany and ethnopharmacology studies

SR Ali, S Kumari, SK Prasad, RS Prasad… - Drug Discovery and …, 2023 - Springer
In order to determine the present state of knowledge on ethnobotany, ethnopharmacology,
and its application to drug development, this work reviews a variety of texts and studies in …

Twenty-five years of natural products research in NuBBE

H Mannochio-Russo, AL Pires dos Santos… - Frontiers in Natural …, 2023 - frontiersin.org
The richness of Brazilian biodiversity translates into a valuable collection of molecules with
biological properties that range from ecological functions to pharmacological properties. For …