Many different strategies can be found in the literature to model organ physiology, tissue
functionality, and disease in vitro; however, most of these models lack the physiological fluid …

Introduction Vascular diseases impart a tremendous burden on healthcare systems in the
United States and across the world. Efforts to improve therapeutic interventions are hindered …

Mesenchymal stem cells have contributed to the continuous progress of tissue engineering
and regenerative medicine. Adipose‐derived stem cells (ADSC) possess many advantages …

Microphysiological and organ‐on‐chip platforms seek to address critical gaps in human
disease models and drug development that underlie poor rates of clinical success for novel …

Interstitial fluid uptake and retention by lymphatic vessels (LVs) play a role in maintaining
interstitial fluid homeostasis. While it is well-established that intraluminal lymphatic valves in …

The use of microfluidics to make mechanical property measurements is increasingly
common. Fabrication of microfluidic devices has enabled various types of flow control and …

Blood and lymphatic vessels are regulators of physiological processes, including
oxygenation and fluid transport. Both vessels are ubiquitous throughout the body and are …

The extracellular matrix (ECM) plays an important regulatory role in the development and
progression of tumoral tissue. Its functions and properties are crucial in determining tumor …

The human thymus is the site of T‐cell maturation and induction of central tolerance.
Hematopoietic stem cell (HSC)‐derived progenitors are recruited to the thymus from the fetal …

The immune system identifies and destroys invading pathogens. However, chronic
inflammation and excessive tissue damage can occur if inflammation is not resolved or if the …