In the present investigation, a totally of 673 newly designed 2, 6-diphenyl piperidin-4-one
derivatives are docked with 2B7N protein of Helicobacter pylori which causes peptic ulcer …

Aim: The discovery of new generation of selective COX-2 inhibitors with potential analgesic
and anti-inflammatory activity and minimal side effects is a major interest. Materials & …

Three-component reaction of polyether-linked bisnaphthaldehyde, ketone derivative, and
ammonium acetate afforded seven new azacrown ethers containing γ-piperidone fragment …

The NSAIDs ibuprofen was chemically conjugated to the PEG‐graft‐β‐CyD with an ester
bond and its aqueous solubility was clearly improved. The preliminary release profile of …

Background: Benzimidazole and piperidine rings are important pharmacophore groups for
drug design studies. Objective: In this study, we aimed to investigate the antidepressant-like …

A convenient asymmetric synthesis of methyl (2S, 3S, 6R)-6-(4-fluorophenyl)-2-(4-
hydroxyphenyl)-piperidine-3-carboxylate is described, starting from Baylis–Hillman adducts …

Background: Schiff bases have a broad spectrum of biological activities like
antiinflammatory, analgesic, antimicrobial, anticonvulsant, antitubercular, anticancer …

In this report the thirteen new compounds including five new heterocyclic ligands and eight
complexes with Cu (II), Zn (II) and Ni (II) ions are presented. The investigation of subsequent …

A potent, eco-friendly approach for converting 2, 6-arylpiperidin-4-ones into their
corresponding oximes in the presence of hydroxylamine hydrochloride and catalysed by …

A series of chalcones of thiazole and thiazolidinone (3a–3j) were synthesized, characterized
and evaluated for anticonvulsant activity. The structures of all the new synthesized …