Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation
PCA van der Wel - Biochemical Society Transactions, 2024 - portlandpress.com
The aggregation of proteins into amyloid-like fibrils is seen in many neurodegenerative
diseases. Recent years have seen much progress in our understanding of these misfolded …
diseases. Recent years have seen much progress in our understanding of these misfolded …
1D Ultrathin Peptoid Nanobelts‐Based Organic‐Inorganic Nanocomposite for Photo‐Controllable Chemo‐Enzymatic Cascade Catalysis
P Wu, P Sui, Z Xu, L Zhu, Y Jia, S Dai… - Advanced Functional …, 2024 - Wiley Online Library
The development of 1D stimuli‐responsive ultrathin organic nanomaterials (UTONMs)‐
based hybrid nanocomposites with tailored functions is necessitated to construct hybrid …
based hybrid nanocomposites with tailored functions is necessitated to construct hybrid …
Azobenzene-Tagged Photopeptides Exhibiting Excellent Selectivity and Light-Induced Cytotoxicity in MCF-7 Cells over HeLa and A549
The precise regulation of proteasome activity has become a focal point in current research,
particularly its implications in cancer treatment. Bortezomib is used for treating multiple …
particularly its implications in cancer treatment. Bortezomib is used for treating multiple …
Photocontrolled Reversible Amyloid Fibril Formation of Parathyroid Hormone-Derived Peptides
Peptide fibrillization is crucial in biological processes such as amyloid-related diseases and
hormone storage, involving complex transitions between folded, unfolded, and aggregated …
hormone storage, involving complex transitions between folded, unfolded, and aggregated …
Spiropyran as Building Block in Peptide Synthesis and Modulation of Photochromic Properties
A Paschold, N Starke, S Rothemund, WH Binder - Organic Letters, 2024 - ACS Publications
Light-controlled triggering of materials requires efficient embedding of molecular
photoswitches into larger molecules. We herein present the synthesis of two new building …
photoswitches into larger molecules. We herein present the synthesis of two new building …
Chiral structures in azobenzene‐containing systems: Construction, regulation, and application
Chirality is a fundamental property in nature, which is essential for the existence and survival
of living organisms. Smart responsive chiroptical materials have garnered increasing …
of living organisms. Smart responsive chiroptical materials have garnered increasing …
Inhibitor-based modulation of huntingtin aggregation reduces fibril toxicity
Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of the
polyglutamine (polyQ) segment in the exon 1 of the huntingtin (HttEx1) protein. This polyQ …
polyglutamine (polyQ) segment in the exon 1 of the huntingtin (HttEx1) protein. This polyQ …
A Photoswitchable Tryptophan Zipper–(Un) folding Fibrils in Seconds
ER Cotroneo, TC Cheng, L Kaltschnee, P Maibach… - 2025 - chemrxiv.org
Peptides and proteins, that have the tendency to form aggregates, are often discussed in the
context of Alz-heimer's, Huntington's, or Parkinson's disease. However, studying …
context of Alz-heimer's, Huntington's, or Parkinson's disease. However, studying …