A systematic review of plants with antibacterial activities: A taxonomic and phylogenetic perspective

F Chassagne, T Samarakoon, G Porras… - Frontiers in …, 2021 - frontiersin.org
Background: Antimicrobial resistance represents a serious threat to human health across the
globe. The cost of bringing a new antibiotic from discovery to market is high and return on …

Ethnobotany, phytochemistry, and biological activities of Psidium guajava in the treatment of diarrhea: a review

C Liu, V Jullian, F Chassagne - Frontiers in Pharmacology, 2024 - frontiersin.org
Psidium guajava: is a tropical tree that is widely used in traditional medicine, especially for
treating diarrhea. While P. guajava has been the subject of numerous reviews, none have …

Antibacterial activity of plant species used for oral health against Porphyromonas gingivalis

DH Carrol, F Chassagne, M Dettweiler, CL Quave - PloS one, 2020 - journals.plos.org
Porphyromonas gingivalis is the keystone pathogen of periodontitis, a chronic inflammatory
disease which causes tooth loss and deterioration of gingiva. Medicinal plants have been …

Efficacy of Rotundic acid and its derivatives as promising natural anticancer triterpenoids: A literature‐based study

MS Bhuia, R Chowdhury, FA Sonia… - Chemistry & …, 2024 - Wiley Online Library
Rotundic acid (RA) is a naturally occurring pentacyclic triterpene with a multitude of
pharmacological activities. The primary emphasis of this study is on summarizing the …

Chemical constituents from Diospyros fragrans Gürke (Ebenaceae)

NSJ Tameye, CM Akak, GB Tabekoueng… - Biochemical Systematics …, 2022 - Elsevier
A new naphtalenone derivative named fragranone, alongside seventeen known
compounds: ten triterpenoids, one monoglycerol, one polyterpenoid, one carotenoid, two …

Improvement of cognitive function in mice by Citrus reticulata var. kinnow via modulation of central cholinergic system and oxidative stress

S Pruthi, K Kaur, V Singh, R Shri - Metabolic Brain Disease, 2021 - Springer
Memory disorders are a result of a number of factors, of which elevated brain oxidative
stress and acetylcholinesterase (AChE) activity are significant hallmarks. A number of Citrus …

[HTML][HTML] Therapeutic Capabilities of Triterpenes and Triterpenoids in Immune and Inflammatory Processes: A Review

M Mantiniotou, V Athanasiadis, D Kalompatsios… - Compounds, 2025 - mdpi.com
Plant-derived secondary metabolites such as triterpenes and triterpenoids are present in a
wide range of plant species. These compounds are particularly attractive due to their …

Tackling nontuberculous mycobacteria by repurposable drugs and potential leads from natural products

P Amruta Adhikrao, G Mayuri Motiram… - Current Topics in …, 2024 - benthamdirect.com
Nontuberculous Mycobacteria (NTM) refer to bacteria other than all Mycobacterium species
that do not cause tuberculosis or leprosy, excluding the species of the Mycobacterium …

Intestinal absorption mechanism of rotundic acid: Involvement of P-gp and OATP2B1

H Shang, Y Sun, Z Wang, Y Zhou, H Yang, X Ci… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Ilicis Rotundae Cortex (IRC), the dried barks of
Ilex rotunda Thunb.(Aquifoliaceae), has been used for the prevention or treatment of colds …

Influence of verapamil on the pharmacokinetics of rotundic acid in rats and its potential mechanism

H Shang, Z Wang, H Ma, Y Sun, X Ci, Y Gu… - Pharmaceutical …, 2021 - Taylor & Francis
Context Rotundic acid (RA), a plant-derived pentacyclic triterpene acid, has been reported to
possess extensive pharmacological activities. The poor bioavailability limits its further …