Lateral pressure in membranes

D Marsh - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1996 - Elsevier
The concept of surface pressure (or lateral pressure) is well known for phospholipid
monolayers at the air-water (or oil-water) interface and, in this case, has a …

A computer perspective of membranes: molecular dynamics studies of lipid bilayer systems

DP Tieleman, SJ Marrink, HJC Berendsen - Biochimica et Biophysica Acta …, 1997 - Elsevier
Knowledge of the structure and dynamics of membranes has traditionally been fragmentary
at the atomic level. This is due partly to the fluid character of membranes under physiological …

Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature

O Berger, O Edholm, F Jähnig - Biophysical journal, 1997 - cell.com
Molecular dynamics simulations of 500 ps were performed on a system consisting of a
bilayer of 64 molecules of the lipid dipalmitoylphosphatidylcholine and 23 water molecules …

Machine learning designs non-hemolytic antimicrobial peptides

A Capecchi, X Cai, H Personne, T Köhler… - Chemical …, 2021 - pubs.rsc.org
Machine learning (ML) consists of the recognition of patterns from training data and offers
the opportunity to exploit large structure–activity databases for drug design. In the area of …

DL_POLY: Application to molecular simulation

W Smith, CW Yong, PM Rodger - Molecular Simulation, 2002 - Taylor & Francis
DL_POLY is a general-purpose molecular dynamics simulation package, which was
developed by Daresbury Laboratory in the mid-1990s for the molecular simulation …

Molecular dynamics simulations of phospholipid bilayers with cholesterol

C Hofsäß, E Lindahl, O Edholm - Biophysical journal, 2003 - cell.com
To investigate the microscopic interactions between cholesterol and lipids in biological
membranes, we have performed a series of molecular dynamics simulations of large …

Mesoscopic undulations and thickness fluctuations in lipid bilayers from molecular dynamics simulations

E Lindahl, O Edholm - Biophysical journal, 2000 - cell.com
Molecular dynamics simulations of fully hydrated Dipalmitoylphosphatidylcholine bilayers,
extending temporal and spatial scales by almost one order of magnitude, are presented. The …

Molecular dynamics of water at the protein− solvent interface

AR Bizzarri, S Cannistraro - The Journal of Physical Chemistry B, 2002 - ACS Publications
The use of molecular dynamics simulation to investigate the properties of hydration water
around proteins is outlined. A variety of structural and dynamical properties of the protein …

Permeation process of small molecules across lipid membranes studied by molecular dynamics simulations

SJ Marrink, HJC Berendsen - The Journal of Physical Chemistry, 1996 - ACS Publications
The transport of small molecules across a phospholipid membrane is studied by molecular
dynamics simulations. The effects of size, hydrophobicity, and asphericity of the penetrants …

A new force field for simulating phosphatidylcholine bilayers

D Poger, WF Van Gunsteren… - Journal of computational …, 2010 - Wiley Online Library
A new force field for the simulation of dipalmitoylphosphatidylcholine (DPPC) in the liquid‐
crystalline, fluid phase at zero surface tension is presented. The structure of the bilayer with …