Narcolepsy is a rare brain disorder that reflects a selective loss or dysfunction of orexin (also
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …

Narcolepsy | New England Journal of Medicine Skip to main content The New England Journal
of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …

Neuropeptides are found in many mammalian CNS neurons where they play key roles in
modulating neuronal activity. In contrast to amino acid transmitter release at the synapse …

Narcolepsy is a sleep disorder caused by deficiency of orexin signaling. However, the
neural mechanisms by which deficient orexin signaling causes the abnormal rapid eye …

The hypothalamus is among the most phylogenetically conserved regions in the vertebrate
brain, reflecting its critical role in maintaining physiological and behavioural homeostasis. By …

Narcolepsy is a sleep disorder characterised by loss of hypothalamic hypocretin (orexin)
neurons. The prevalence of narcolepsy is about 30 per 100 000 people, and typical age at …

Hypocretin/orexin neurons are distributed restrictively in the hypothalamus, a brain region
known to orchestrate diverse functions including sleep, reward processing, food intake …

The lateral hypothalamus (LH) is a functionally and anatomically complex brain region that
is involved in the regulation of many behavioral and physiological processes including …

* Also available as audiobook! Psychology 2e is designed to meet scope and sequence
requirements for the single-semester introduction to psychology course. The book offers a …

Highlights•Narcolepsy is caused by the loss of hypocretin-producing neurons in the
brain.•HLA DQB1* 06: 02 association suggests an autoimmune basis for narcolepsy.• …