Methodologies to isolate and purify clinical grade extracellular vesicles for medical applications

A Akbar, F Malekian, N Baghban, SP Kodam, M Ullah - Cells, 2022 - mdpi.com
The use of extracellular vesicles (EV) in nano drug delivery has been demonstrated in many
previous studies. In this study, we discuss the sources of extracellular vesicles, including …

Exosome engineering for efficient and targeted drug delivery: Current status and future perspective

F Malekian, A Shamsian, SP Kodam… - The Journal of …, 2023 - Wiley Online Library
Exosomes are membrane‐bound vesicles that are released by most cells. They carry
nucleic acids, cytokines, growth factors, proteins, lipids, and metabolites. They are …

Diagnostic and therapeutic potential of extracellular vesicles

SP Kodam, M Ullah - Technology in Cancer Research & …, 2021 - journals.sagepub.com
Extracellular vesicles (EVs) are naturally phospholipid enclosed nanovesicles released by
many cells in the body. They are stable in circulation, have low immunogenicity, and act as …

Chickpeas' tolerance of drought and heat: Current knowledge and next steps

E Karalija, C Vergata, MF Basso, M Negussu, M Zaccai… - Agronomy, 2022 - mdpi.com
The global increase in temperature and associated meteorological disruptions, such as the
earlier onset of high temperatures and disruptions in precipitation, are becoming severely …

[HTML][HTML] Role of CD9 sensing, AI, and exosomes in cellular communication of cancer

N Baghban, SP Kodam, M Ullah - … journal of stem cell research and …, 2023 - ncbi.nlm.nih.gov
Exosomes are small membrane-bound vesicles that are released by various types of cells,
including cancer cells, and play a role in intercellular communication. CD9 is a protein that is …

Different sourced extracellular vesicles and their potential applications in clinical treatments

L Bahmani, M Ullah - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) include a heterogeneous group of natural cell-derived
nanostructures that are increasingly regarded as promising biotherapeutic agents and drug …

Cellular functions of heat shock protein 20 (HSPB6) in cancer: A review

Y Wu, J Zhao, Y Tian, H ** - Cellular Signalling, 2023 - Elsevier
Heat shock proteins (HSP) are a large family of peptide proteins that are widely found in
cells. Studies have shown that the expression and function of HSPs in cells are very …

[HTML][HTML] SAR-CoV-2 infection, emerging new variants and the role of activation induced cytidine deaminase (AID) in lasting immunity

A Ullah, N Mabood, M Maqbool, L Khan, M Khan… - Saudi Pharmaceutical …, 2021 - Elsevier
As the world faces a fourth COVID-19 spike, scientists are learning a lot more about the new
SARS-CoV-2 strains that were previously unknown. Currently, the Delta versions of SARS …

[HTML][HTML] Global requirements for manufacturing and validation of clinical grade extracellular vesicles

A Thakur, D Rai - The Journal of Liquid Biopsy, 2024 - Elsevier
Extracellular vesicles (EVs) are nanovesicles released from different cell types from biofluids
such as blood, urine, and cerebrospinal fluid. They vary in size and biomarkers, and their …

An overview of heat stress in Chickpea (Cicer arietinum L.): effects, mechanisms and diverse molecular breeding approaches for enhancing resilience and …

M Naveed, M Aslam, SR Ahmed, DKY Tan… - Molecular …, 2025 - Springer
Chickpea (Cicer arietinum. L) holds the esteemed position of being the second most
cultivated and consumed legume crop globally. Nevertheless, both biotic and abiotic …