Epidemiological studies have shown a clear association between maternal infection and
schizophrenia or autism in the progeny. Animal models have revealed maternal immune …

N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …

There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

Background Bipolar disorder may be associated with peripheral immune system
dysfunction; however, results in individual studies are conflicting. Our aim was to …

Background Immune dysfunction, including monocytosis and increased blood levels of
interleukin-1, interleukin-6 and tumour necrosis factor α has been observed during acute …

Introduction Peripheral levels of inflammatory markers are elevated in major depressive
disorder (MDD). Selective serotonin reuptake inhibitors (SSRIs) affect levels of inflammatory …

There is an expanding field of research investigating the benefits of alternatives to current
pharmacological therapies in psychiatry. N-acetylcysteine (NAC) is emerging as a useful …

Review on the key role for activated microglia and monocytes in the pathogenesis of bipolar
disorder and schizophrenia. This review describes a key role for mononuclear phagocytes in …

Autoimmunity, gastrointestinal (GI) disorders and schizophrenia have been associated with
one another for a long time. This paper reviews these connections and provides a context by …

Background Schizophrenia might share intrinsic inflammatory disease pathways with type 2
diabetes. We aimed to assess whether first-episode psychosis, which could be described as …