Mitochondrial and metabolic dysfunction in ageing and age-related diseases
Organismal ageing is accompanied by progressive loss of cellular function and systemic
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …
Facing up to the global challenges of ageing
Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …
people experience little ill health, a trait that should be extended to the general population …
Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank …
Objective To investigate the association of grip strength with disease specific incidence and
mortality and whether grip strength enhances the prediction ability of an established office …
mortality and whether grip strength enhances the prediction ability of an established office …
Muscular strength as a predictor of all-cause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million …
Objectives The aims of the present systematic review and meta-analysis were to determine
the relationship between muscular strength and all-cause mortality risk and to examine the …
the relationship between muscular strength and all-cause mortality risk and to examine the …
Leading a meaningful life at older ages and its relationship with social engagement, prosperity, health, biology, and time use
The sense that one is living a worthwhile and meaningful life is fundamental to human
flourishing and subjective well-being. Here, we investigate the wider implications of feeling …
flourishing and subjective well-being. Here, we investigate the wider implications of feeling …
The genetics of aging: a vertebrate perspective
Aging negatively impacts vitality and health. Many genetic pathways that regulate aging
were discovered in invertebrates. However, the genetics of aging is more complex in …
were discovered in invertebrates. However, the genetics of aging is more complex in …
Association of grip strength with risk of all-cause mortality, cardiovascular diseases, and cancer in community-dwelling populations: a meta-analysis of prospective …
Y Wu, W Wang, T Liu, D Zhang - Journal of the American Medical Directors …, 2017 - Elsevier
Objectives Grip strength has been linked to risk of adverse health outcomes. This study
aimed to quantitatively assess the associations between grip strength and risk of all-cause …
aimed to quantitatively assess the associations between grip strength and risk of all-cause …
A proposed panel of biomarkers of healthy ageing
Background There is no criterion reference for assessing healthy ageing and this creates
difficulties when conducting and comparing research on ageing across studies. A cardinal …
difficulties when conducting and comparing research on ageing across studies. A cardinal …
Effects of concurrent strength and endurance training on measures of physical fitness in healthy middle-aged and older adults: a systematic review with meta-analysis
A Markov, L Hauser, H Chaabene - Sports Medicine, 2023 - Springer
Background There is evidence that in older adults the combination of strength training (ST)
and endurance training (ET)(ie, concurrent training [CT]) has similar effects on measures of …
and endurance training (ET)(ie, concurrent training [CT]) has similar effects on measures of …
Associations between polypharmacy and cognitive and physical capability: a British birth cohort study
Objectives To investigate longitudinal associations between polypharmacy and cognitive
and physical capability and to determine whether these associations differ with cumulative …
and physical capability and to determine whether these associations differ with cumulative …