Active turbulence

R Alert, J Casademunt, JF Joanny - Annual Review of …, 2022 - annualreviews.org
Active fluids exhibit spontaneous flows with complex spatiotemporal structure, which have
been observed in bacterial suspensions, sperm cells, cytoskeletal suspensions, self …

Material approaches to active tissue mechanics

W **, TB Saw, D Delacour, CT Lim… - Nature Reviews Materials, 2019 - nature.com
Communities of epithelial cells communicate through intercellular interactions, allowing
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …

State of cell unjamming correlates with distant metastasis in cancer patients

P Gottheil, J Lippoldt, S Grosser, F Renner, M Saibah… - Physical Review X, 2023 - APS
Pathological morphological changes in tumor tissue enable collective cancer cell
unjamming, a cellular motility transition. However, fundamental questions remain: Is …

Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers

L Balasubramaniam, A Doostmohammadi, TB Saw… - Nature materials, 2021 - nature.com
Actomyosin machinery endows cells with contractility at a single-cell level. However, within a
monolayer, cells can be contractile or extensile based on the direction of pushing or pulling …

Topological defects in epithelia govern cell death and extrusion

TB Saw, A Doostmohammadi, V Nier, L Kocgozlu… - Nature, 2017 - nature.com
Epithelial tissues (epithelia) remove excess cells through extrusion, preventing the
accumulation of unnecessary or pathological cells. The extrusion process can be triggered …

Topological defects in confined populations of spindle-shaped cells

G Duclos, C Erlenkämper, JF Joanny, P Silberzan - Nature Physics, 2017 - nature.com
Most spindle-shaped cells (including smooth muscles and sarcomas) organize in vivo into
well-aligned 'nematic'domains,,, creating intrinsic topological defects that may be used to …

A growing bacterial colony in two dimensions as an active nematic

D Dell'Arciprete, ML Blow, AT Brown… - Nature …, 2018 - nature.com
How a single bacterium becomes a colony of many thousand cells is important in
biomedicine and food safety. Much is known about the molecular and genetic bases of this …

Universal scaling of active nematic turbulence

R Alert, JF Joanny, J Casademunt - Nature Physics, 2020 - nature.com
A landmark of turbulence is the emergence of universal scaling laws, such as Kolmogorov's
E (q)~ q− 5∕ 3 scaling of the kinetic energy spectrum of inertial turbulence with the …

Emergence of active turbulence in microswimmer suspensions due to active hydrodynamic stress and volume exclusion

K Qi, E Westphal, G Gompper, RG Winkler - Communications Physics, 2022 - nature.com
Microswimmers exhibit an intriguing, highly-dynamic collective motion with large-scale
swirling and streaming patterns, denoted as active turbulence–reminiscent of classical high …

Emergence of active nematic behavior in monolayers of isotropic cells

R Mueller, JM Yeomans, A Doostmohammadi - Physical review letters, 2019 - APS
There is now growing evidence of the emergence and biological functionality of liquid crystal
features, including nematic order and topological defects, in cellular tissues. However, how …