A review of feature selection and feature extraction methods applied on microarray data

ZM Hira, DF Gillies - Advances in bioinformatics, 2015 - Wiley Online Library
We summarise various ways of performing dimensionality reduction on high‐dimensional
microarray data. Many different feature selection and feature extraction methods exist and …

Gene reduction and machine learning algorithms for cancer classification based on microarray gene expression data: A comprehensive review

S Osama, H Shaban, AA Ali - Expert Systems with Applications, 2023 - Elsevier
Disease diagnosis and prediction methods in biotechnology and medicine have significantly
advanced over time. Consequently, analyzing raw gene expression is crucial for identifying …

Interpretation of T cell states from single-cell transcriptomics data using reference atlases

M Andreatta, J Corria-Osorio, S Müller, R Cubas… - Nature …, 2021 - nature.com
Single-cell RNA sequencing (scRNA-seq) has revealed an unprecedented degree of
immune cell diversity. However, consistent definition of cell subtypes and cell states across …

The Escherichia coli transcriptome mostly consists of independently regulated modules

AV Sastry, Y Gao, R Szubin, Y Hefner, S Xu… - Nature …, 2019 - nature.com
Underlying cellular responses is a transcriptional regulatory network (TRN) that modulates
gene expression. A useful description of the TRN would decompose the transcriptome into …

[HTML][HTML] Enter the matrix: factorization uncovers knowledge from omics

GL Stein-O'Brien, R Arora, AC Culhane, AV Favorov… - Trends in Genetics, 2018 - cell.com
Omics data contain signals from the molecular, physical, and kinetic inter-and intracellular
interactions that control biological systems. Matrix factorization (MF) techniques can reveal …

Principles and methods of integrative genomic analyses in cancer

VN Kristensen, OC Lingjærde, HG Russnes… - Nature Reviews …, 2014 - nature.com
Combined analyses of molecular data, such as DNA copy-number alteration, mRNA and
protein expression, point to biological functions and molecular pathways being deregulated …

Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

PW Burridge, YF Li, E Matsa, H Wu, SG Ong… - Nature medicine, 2016 - nature.com
Doxorubicin is an anthracycline chemotherapy agent effective in treating a wide range of
malignancies, but it causes a dose-related cardiotoxicity that can lead to heart failure in a …

Knowledge discovery in medicine: Current issue and future trend

N Esfandiari, MR Babavalian, AME Moghadam… - Expert Systems with …, 2014 - Elsevier
Data mining is a powerful method to extract knowledge from data. Raw data faces various
challenges that make traditional method improper for knowledge extraction. Data mining is …

[HTML][HTML] Detection of mental stress through EEG signal in virtual reality environment

D Kamińska, K Smółka, G Zwoliński - Electronics, 2021 - mdpi.com
This paper investigates the use of an electroencephalogram (EEG) signal to classify a
subject's stress level while using virtual reality (VR). For this purpose, we designed an …

Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease

XC Morgan, B Kabakchiev, L Waldron, AD Tyler… - Genome biology, 2015 - Springer
Background Pouchitis is common after ileal pouch-anal anastomosis (IPAA) surgery for
ulcerative colitis (UC). Similar to inflammatory bowel disease (IBD), both host genetics and …