Human tendon adaptation in response to mechanical loading: a systematic review and meta-analysis of exercise intervention studies on healthy adults

S Bohm, F Mersmann, A Arampatzis - Sports medicine-open, 2015 - Springer
Background The present article systematically reviews recent literature on the in vivo
adaptation of asymptomatic human tendons following increased chronic mechanical …

The materials science of collagen

VR Sherman, W Yang, MA Meyers - Journal of the mechanical behavior of …, 2015 - Elsevier
Collagen is the principal biopolymer in the extracellular matrix of both vertebrates and
invertebrates. It is produced in specialized cells (fibroblasts) and extracted into the body by a …

Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy

R Rezakhaniha, A Agianniotis, JTC Schrauwen… - … and modeling in …, 2012 - Springer
Mechanical properties of the adventitia are largely determined by the organization of
collagen fibers. Measurements on the waviness and orientation of collagen, particularly at …

Role of biomaterials and controlled architecture on tendon/ligament repair and regeneration

YJ No, M Castilho, Y Ramaswamy… - Advanced …, 2020 - Wiley Online Library
Engineering synthetic scaffolds to repair and regenerate ruptured native tendon and
ligament (T/L) tissues is a significant engineering challenge due to the need to satisfy both …

[BOOK][B] Tissue mechanics

SC Cowin, SB Doty - 2007 - Springer
The reader of this chapter may draw inspiration from the following quote from research
biologist Albert Harris (Harris, 1994):“Systems of interacting forces and stimuli don't have to …

[HTML][HTML] Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides

JL Zitnay, Y Li, Z Qin, BH San, B Depalle… - Nature …, 2017 - nature.com
Mechanical injury to connective tissue causes changes in collagen structure and material
behaviour, but the role and mechanisms of molecular damage have not been established. In …

Collagen structure of tendon relates to function

M Franchi, A Trirè, M Quaranta… - The Scientific World …, 2007 - Wiley Online Library
A tendon is a tough band of fibrous connective tissue that connects muscle to bone,
designed to transmit forces and withstand tension during muscle contraction. Tendon may …

Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile …

SP Lake, KS Miller, DM Elliott… - Journal of Orthopaedic …, 2009 - Wiley Online Library
Tendon exhibits nonlinear stress–strain behavior that may be partly due to movement of
collagen fibers through the extracellular matrix. While a few techniques have been …

Tissue-specific parameters for the design of ECM-mimetic biomaterials

OR Tonti, H Larson, SN Lipp, CM Luetkemeyer… - Acta biomaterialia, 2021 - Elsevier
The extracellular matrix (ECM) is a complex network of biomolecules that mechanically and
biochemically directs cell behavior and is crucial for maintaining tissue function and health …

Effect of fiber orientation and strain rate on the nonlinear uniaxial tensile material properties of tendon

HA Lynch, W Johannessen, JP Wu… - J. Biomech …, 2003 - asmedigitalcollection.asme.org
Tendons are exposed to complex loading scenarios that can only be quantified by
mathematical models, requiring a full knowledge of tendon mechanical properties. This …