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Engineering precision nanoparticles for drug delivery
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
[HTML][HTML] Biomedical applications of microfluidic devices: a review
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …
applications to support fluid mixing, particle manipulations, and signal detection. Passive …
Therapeutic potential of bacteriophage endolysins for infections caused by Gram-positive bacteria
H Liu, Z Hu, M Li, Y Yang, S Lu, X Rao - Journal of biomedical science, 2023 - Springer
Abstract Gram-positive (G+) bacterial infection is a great burden to both healthcare and
community medical resources. As a result of the increasing prevalence of multidrug-resistant …
community medical resources. As a result of the increasing prevalence of multidrug-resistant …
The advantages and challenges of using endolysins in a clinical setting
Antibiotic-resistant pathogens are increasingly more prevalent and problematic. Traditional
antibiotics are no longer a viable option for dealing with these multidrug-resistant microbes …
antibiotics are no longer a viable option for dealing with these multidrug-resistant microbes …
Multidrug-resistant bacteria and alternative methods to control them: an overview
R Vivas, AAT Barbosa, SS Dolabela… - Microbial Drug …, 2019 - liebertpub.com
Antibiotic resistance is one of the greatest challenges in the health system nowadays,
representing a serious problem for public health. Initially, antibiotic-resistant strains were …
representing a serious problem for public health. Initially, antibiotic-resistant strains were …
[HTML][HTML] Phage-encoded endolysins
Due to the global emergence of antibiotic resistance, there has been an increase in
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …
[HTML][HTML] Treating bacterial infections with bacteriophage-based enzybiotics: in vitro, in vivo and clinical application
Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …
Recombinant endolysins as potential therapeutics against antibiotic-resistant Staphylococcus aureus: current status of research and novel delivery strategies
H Haddad Kashani, M Schmelcher… - Clinical microbiology …, 2018 - journals.asm.org
Staphylococcus aureus is one of the most common pathogens of humans and animals,
where it frequently colonizes skin and mucosal membranes. It is of major clinical importance …
where it frequently colonizes skin and mucosal membranes. It is of major clinical importance …
Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing
Orthopedic implant infections are a significant clinical problem, with current therapies limited
to surgical debridement and systemic antibiotic regimens. Lysostaphin is a bacteriolytic …
to surgical debridement and systemic antibiotic regimens. Lysostaphin is a bacteriolytic …
Synthetic biology of modular endolysins
Endolysins and their derivatives have emerged in recent years as a novel class of
antibacterials, which have now entered the clinical phases. Their rapid mode-of-action and …
antibacterials, which have now entered the clinical phases. Their rapid mode-of-action and …