Cellular membranes function as permeability barriers that separate cells from the external
environment or partition cells into distinct compartments. These membranes are lipid …

The Martini model, a coarse‐grained force field for molecular dynamics simulations, has
been around for nearly two decades. Originally developed for lipid‐based systems by the …

Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

Mechanosensitive (MS) ion channels are a ubiquitous type of molecular force sensor
sensing forces from the surrounding bilayer. The profound structural diversity in these …

Tumor cellular metabolism exhibits distinguishing features that collectively enhance
biomass synthesis while maintaining redox balance and cellular homeostasis. These …

TMEM41B and VMP1 are integral membrane proteins of the endoplasmic reticulum (ER)
and regulate the formation of autophagosomes, lipid droplets (LDs), and lipoproteins …

The dual functions of TMEM16F as Ca2+-activated ion channel and lipid scramblase raise
intriguing questions regarding their molecular basis. Intrigued by the ability of the FDA …

Biomembranes are complex materials composed of lipids and proteins that
compartmentalize biochemistry. They are actively remodeled in response to physical and …

Glycerophospholipids are synthesized primarily in the cytosolic leaflet of the endoplasmic
reticulum (ER) membrane and must be equilibrated between bilayer leaflets to allow the ER …

How amphipathic phospholipids are shuttled between the membrane bilayer remains an
essential but elusive process, particularly at the endoplasmic reticulum (ER). One prominent …