Animal genomes are folded in topologically associating domains (TADs) that have been
linked to the regulation of the genes they contain by constraining regulatory interactions …

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily
conserved morphology and genome structure, has led to its use as a model for studies of …

Vertebrates have greatly elaborated the basic chordate body plan and evolved highly
distinctive genomes that have been sculpted by two whole-genome duplications. Here we …

It has been speculated that before vertebrates evolved somatic diversity-based adaptive
immunity, the germline-encoded diversity of innate immunity may have been more …

All vertebrate brains develop following a common Bauplan defined by anteroposterior (AP)
and dorsoventral (DV) subdivisions, characterized by largely conserved differential …

Abstract The HoxA and HoxD gene clusters of jawed vertebrates are organized into bipartite
three-dimensional chromatin structures that separate long-range regulatory inputs coming …

FGF signaling is one of the few cell–cell signaling pathways conserved among all
metazoans. The diversity of FGF gene content among different phyla suggests that evolution …

Chordates are divided into three subphyla: Vertebrata, Tunicata, and Cephalochordata.
Phylogenetically, the Cephalochordata, more commonly known as lancelets or amphioxus …

Cephalochordates and tunicates represent the only two groups of invertebrate chordates,
and extant cephalochordates–commonly known as amphioxus or lancelets–are considered …

This review article gathers the available information on the use of embryo-tests as high-
throughput tools for toxicity screening, hazard assessment and prioritization of new and …