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Plant serine protease inhibitors: biotechnology application in agriculture and molecular farming
The serine protease inhibitors (SPIs) are widely distributed in living organisms like bacteria,
fungi, plants, and humans. The main function of SPIs as protease enzymes is to regulate the …
fungi, plants, and humans. The main function of SPIs as protease enzymes is to regulate the …
Transgene expression in microalgae—from tools to applications
Microalgae comprise a biodiverse group of photosynthetic organisms that reside in water
sources and sediments. The green microalgae Chlamydomonas reinhardtii was adopted as …
sources and sediments. The green microalgae Chlamydomonas reinhardtii was adopted as …
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens
Antimicrobial peptides (AMPs) are promising next-generation antibiotics that can be used to
combat drug-resistant pathogens. However, the high cost involved in AMP synthesis and …
combat drug-resistant pathogens. However, the high cost involved in AMP synthesis and …
Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules
Plant cell culture systems were initially explored for use in commercial synthesis of several
high‐value secondary metabolites, allowing for sustainable production that was not limited …
high‐value secondary metabolites, allowing for sustainable production that was not limited …
Plant molecular farming: much more than medicines
M Tschofen, D Knopp, E Hood… - Annual Review of …, 2016 - annualreviews.org
Plants have emerged as commercially relevant production systems for pharmaceutical and
nonpharmaceutical products. Currently, the commercially available nonpharmaceutical …
nonpharmaceutical products. Currently, the commercially available nonpharmaceutical …
Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures
“Molecular farming” in plants with significant advantages in cost and safety is touted as a
promising platform for the production of complex pharmaceutical proteins. While whole-plant …
promising platform for the production of complex pharmaceutical proteins. While whole-plant …
Hairy root type plant in vitro systems as sources of bioactive substances
Abstract “Hairy root” systems, obtained by transforming plant tissues with the “natural genetic
engineer” Agrobacterium rhizogenes, have been known for more than three decades. To …
engineer” Agrobacterium rhizogenes, have been known for more than three decades. To …
Production of heterologous proteins in plants: strategies for optimal expression
PN Desai, N Shrivastava, H Padh - Biotechnology advances, 2010 - Elsevier
Plants are a promising expression system for the production of heterologous proteins,
especially therapeutic proteins. Currently the majority of therapeutic proteins are produced …
especially therapeutic proteins. Currently the majority of therapeutic proteins are produced …
Pharmaceutically active natural product synthesis and supply via plant cell culture technology
The chemical diversity of plant-derived natural products allows them to function in a
multitude of ways including flavor enhancers, agricultural chemicals, and importantly, human …
multitude of ways including flavor enhancers, agricultural chemicals, and importantly, human …
Viral vectors for production of recombinant proteins in plants
Global demand for recombinant proteins has steadily accelerated for the last 20 years.
These recombinant proteins have a wide range of important applications, including vaccines …
These recombinant proteins have a wide range of important applications, including vaccines …