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Bile acid derivatives: From old molecules to a new potent therapeutic use: An overview
M Blanchet, JM Brunel - Current Medicinal Chemistry, 2018 - ingentaconnect.com
Bile acids or bile salts, belong to a large family of biological steroid derivatives found
predominantly in the bile of mammals and other vertebrates. These amphipathic molecules …
predominantly in the bile of mammals and other vertebrates. These amphipathic molecules …
Investigation of the interaction between amodiaquine and human serum albumin by fluorescence spectroscopy and molecular modeling
The interaction of amodiaquine (AQ) with human serum albumin (HSA) has been studied by
fluorescence spectroscopy. Based on the sign and magnitude of the enthalpy and entropy …
fluorescence spectroscopy. Based on the sign and magnitude of the enthalpy and entropy …
Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding …
B Demoro, RFM De Almeida, F Marques… - Dalton …, 2013 - pubs.rsc.org
Four complexes combining the {Ru (p-cym)} moiety (p-cym= para-cymene) with
thiosemicarbazone (TSC) ligands containing the 5-nitrofuryl pharmacophore were …
thiosemicarbazone (TSC) ligands containing the 5-nitrofuryl pharmacophore were …
[HTML][HTML] Evaluation of solute binding to proteins and intra-protein distances from steady state fluorescence measurements
Steady state fluorescence measurements, due to their relative simplicity and fast and easy
implementation, are one of the most employed techniques for evaluating the non-covalent …
implementation, are one of the most employed techniques for evaluating the non-covalent …
Development and First Clinical Use of an Extracorporeal Artificial Multiorgan System in Acute-on-Chronic Liver Failure Patients
S Ahmad, A Novokhodko, IW Liou, NC Smith… - ASAIO …, 2024 - journals.lww.com
Multiple organ failure (MOF) is a common and deadly condition. Patients with liver cirrhosis
with acute-on-chronic liver failure (AOCLF) are particularly susceptible. Excess fluid …
with acute-on-chronic liver failure (AOCLF) are particularly susceptible. Excess fluid …
[HTML][HTML] Denaturation studies on bovine serum albumin–bile salt system: Bile salt stabilizes bovine serum albumin through hydrophobicity
K Malarkani, I Sarkar, S Selvam - Journal of Pharmaceutical Analysis, 2018 - Elsevier
Protein denaturation is under intensive research, since it leads to neurological disorders of
severe consequences. Avoiding denaturation and stabilizing the proteins in their native state …
severe consequences. Avoiding denaturation and stabilizing the proteins in their native state …
Enantioselective resolution of chiral drugs using BSA functionalized magnetic nanoparticles
Y Fu, T Huang, B Chen, J Shen, X Duan… - Separation and …, 2013 - Elsevier
Bovine serum albumin (BSA) anchored on the surface of magnetic Fe3O4 nanoparticles
(MNPs) were prepared using electrostatic adsorption and studied as a new magnetically …
(MNPs) were prepared using electrostatic adsorption and studied as a new magnetically …
Unveiling the aggregation behavior of doxorubicin hydrochloride in aqueous solution of 1-Octyl-3-methylimidazolium chloride and the effect of bile salt on these …
In this article, we have unveiled the aggregation behavior of a potent chemotherapeutic
drug, doxorubicin hydrochloride (Dox) in a well-known imidazolium based surface active …
drug, doxorubicin hydrochloride (Dox) in a well-known imidazolium based surface active …
Increased selectivity of sodium deoxycholate to around Tryptophan213 in bovine serum albumin upon micellization as revealed by singular value decomposition for …
In the present study, we investigated the effect of bile salts (sodium deoxycholate, NaDC) on
the conformation of a globular protein (bovine serum albumin, BSA). The two Tryptophan …
the conformation of a globular protein (bovine serum albumin, BSA). The two Tryptophan …
Identification and characterization of a single high‐affinity fatty acid binding site in human serum albumin
L Wenskowsky, H Schreuder, V Derdau… - Angewandte …, 2018 - Wiley Online Library
A single high‐affinity fatty acid binding site in the important human transport protein serum
albumin (HSA) is identified and characterized using an NBD (7‐nitrobenz‐2‐oxa‐1, 3‐diazol …
albumin (HSA) is identified and characterized using an NBD (7‐nitrobenz‐2‐oxa‐1, 3‐diazol …