Bile acid derivatives: From old molecules to a new potent therapeutic use: An overview

M Blanchet, JM Brunel - Current Medicinal Chemistry, 2018 - ingentaconnect.com
Bile acids or bile salts, belong to a large family of biological steroid derivatives found
predominantly in the bile of mammals and other vertebrates. These amphipathic molecules …

Investigation of the interaction between amodiaquine and human serum albumin by fluorescence spectroscopy and molecular modeling

F Samari, M Shamsipur, B Hemmateenejad… - European journal of …, 2012 - Elsevier
The interaction of amodiaquine (AQ) with human serum albumin (HSA) has been studied by
fluorescence spectroscopy. Based on the sign and magnitude of the enthalpy and entropy …

Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding …

B Demoro, RFM De Almeida, F Marques… - Dalton …, 2013 - pubs.rsc.org
Four complexes combining the {Ru (p-cym)} moiety (p-cym= para-cymene) with
thiosemicarbazone (TSC) ligands containing the 5-nitrofuryl pharmacophore were …

[HTML][HTML] Evaluation of solute binding to proteins and intra-protein distances from steady state fluorescence measurements

E Alarcón, A Aspée, EB Abuin, EA Lissi - Journal of Photochemistry and …, 2012 - Elsevier
Steady state fluorescence measurements, due to their relative simplicity and fast and easy
implementation, are one of the most employed techniques for evaluating the non-covalent …

Development and First Clinical Use of an Extracorporeal Artificial Multiorgan System in Acute-on-Chronic Liver Failure Patients

S Ahmad, A Novokhodko, IW Liou, NC Smith… - ASAIO …, 2024 - journals.lww.com
Multiple organ failure (MOF) is a common and deadly condition. Patients with liver cirrhosis
with acute-on-chronic liver failure (AOCLF) are particularly susceptible. Excess fluid …

[HTML][HTML] Denaturation studies on bovine serum albumin–bile salt system: Bile salt stabilizes bovine serum albumin through hydrophobicity

K Malarkani, I Sarkar, S Selvam - Journal of Pharmaceutical Analysis, 2018 - Elsevier
Protein denaturation is under intensive research, since it leads to neurological disorders of
severe consequences. Avoiding denaturation and stabilizing the proteins in their native state …

Enantioselective resolution of chiral drugs using BSA functionalized magnetic nanoparticles

Y Fu, T Huang, B Chen, J Shen, X Duan… - Separation and …, 2013 - Elsevier
Bovine serum albumin (BSA) anchored on the surface of magnetic Fe3O4 nanoparticles
(MNPs) were prepared using electrostatic adsorption and studied as a new magnetically …

Unveiling the aggregation behavior of doxorubicin hydrochloride in aqueous solution of 1-Octyl-3-methylimidazolium chloride and the effect of bile salt on these …

A Pyne, S Kundu, P Banerjee, N Sarkar - Langmuir, 2018 - ACS Publications
In this article, we have unveiled the aggregation behavior of a potent chemotherapeutic
drug, doxorubicin hydrochloride (Dox) in a well-known imidazolium based surface active …

Increased selectivity of sodium deoxycholate to around Tryptophan213 in bovine serum albumin upon micellization as revealed by singular value decomposition for …

Y Kurosawa, Y Otsuka, S Goto - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
In the present study, we investigated the effect of bile salts (sodium deoxycholate, NaDC) on
the conformation of a globular protein (bovine serum albumin, BSA). The two Tryptophan …

Identification and characterization of a single high‐affinity fatty acid binding site in human serum albumin

L Wenskowsky, H Schreuder, V Derdau… - Angewandte …, 2018 - Wiley Online Library
A single high‐affinity fatty acid binding site in the important human transport protein serum
albumin (HSA) is identified and characterized using an NBD (7‐nitrobenz‐2‐oxa‐1, 3‐diazol …