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Novel 1, 2, 4‐Triazoles as Antifungal Agents
Z Kazeminejad, M Marzi, A Shiroudi… - BioMed Research …, 2022 - Wiley Online Library
The development of innovative antifungal agents is essential. Some fungicidal agents are no
longer effective due to resistance development, various side effects, and high toxicity …
longer effective due to resistance development, various side effects, and high toxicity …
[HTML][HTML] Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review
M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …
due to the special problems they have faced, such as their increasing diversity and …
1, 2, 3-Triazoles of 8-hydroxyquinoline and HBT: Synthesis and studies (DNA binding, antimicrobial, molecular docking, ADME, and DFT)
A new series of 1, 2, 3-triazole hybrids containing either 2-or 4-hydroxyphenyl benzothiazole
(2-or 4-HBT) and naphthalen-1-ol or 8-hydroxyquinoline (8-HQ) was synthesized in high …
(2-or 4-HBT) and naphthalen-1-ol or 8-hydroxyquinoline (8-HQ) was synthesized in high …
Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents
MM Morcoss, MN El Shimaa, RA Ibrahem… - Bioorganic …, 2020 - Elsevier
Herein, novel three series of benzimidazole scaffold bearing hydrazone, 1, 2, 4-triazole and
1, 3, 4-oxadiazole moieties 1-3, 4a-j, 6a-c and 7 derivatives were designed, synthesized and …
1, 3, 4-oxadiazole moieties 1-3, 4a-j, 6a-c and 7 derivatives were designed, synthesized and …
Synthesis, structural investigations, DFT, molecular docking and antifungal studies of transition metal complexes with benzothiazole based Schiff base ligands
A novel series of complexes of the type,[ML 2]. nH 2 O,[where L= 2-(α-methyl salicylidene–
2′-imino) aminobenzo thiazole (HMAB), 2-(α-phenyl salicylidene–2′-imino) aminobenzo …
2′-imino) aminobenzo thiazole (HMAB), 2-(α-phenyl salicylidene–2′-imino) aminobenzo …
Exploration of Remarkably Potential Multitarget-Directed N-Alkylated-2-(substituted phenyl)-1H-benzimidazole Derivatives as Antiproliferative, Antifungal, and …
Improving lipophilicity for drugs to penetrate the lipid membrane and decreasing bacterial
and fungal coinfections for patients with cancer pose challenges in the drug development …
and fungal coinfections for patients with cancer pose challenges in the drug development …
Fluorescent 7-azaindole N-linked 1, 2, 3-triazole: synthesis and study of antimicrobial, molecular docking, ADME and DFT properties
Two libraries of biologically essential and fluorescent 7-azaindole N-linked benzyl 1, 2, 3-
triazole (4a–4i) and 7-azaindole N-linked phenyl 1, 2, 3-triazole (4j–4q) hybrids have been …
triazole (4a–4i) and 7-azaindole N-linked phenyl 1, 2, 3-triazole (4j–4q) hybrids have been …
Evaluation of quinoxaline derivatives as potential ergosterol biosynthesis inhibitors: design, synthesis, ADMET, molecular docking studies, and antifungal activities
Because of the increased infection incidence and the advent of medication resistance, fungi
have become a severe medical problem. Ergosterol is a structural component of the fungal …
have become a severe medical problem. Ergosterol is a structural component of the fungal …
Synthesis, molecular modeling, quantum mechanical calculations and ADME estimation studies of benzimidazole-oxadiazole derivatives as potent antifungal agents
In this study, a series of new 3-((5-(4-(5-substitue-1H-benz [d] imidazol-2-yl) phenyl)-1, 3, 4-
oxadiazol-2-yl) thio)-1-phenyl propane-1-on (4a-4d) derivatives has been designed and …
oxadiazol-2-yl) thio)-1-phenyl propane-1-on (4a-4d) derivatives has been designed and …
Synthesis, antifungal studies, molecular docking, ADME and DNA interaction studies of 4-hydroxyphenyl benzothiazole linked 1, 2, 3-triazoles
In search of new bioactive 1, 2, 3-triazole hybrids, some 4-hydroxyphenyl benzothiazole (4-
HBT) linked 1, 2, 3-triazole with varying lengths of alkyl spacers were synthesized from …
HBT) linked 1, 2, 3-triazole with varying lengths of alkyl spacers were synthesized from …