A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery

B Kumar, M Pandey, R Aggarwal, PK Sahoo - Future Journal of …, 2022 - Springer
Background Transdermal drug delivery is one of the most widely used drug administration
routes, which offer several advantages over other routes of drug delivery. The apical layer of …

[HTML][HTML] Ethosomes: a promising drug delivery platform for transdermal application

B Zhan, J Wang, H Li, K **ao, X Fang, Y Shi, Y Jia - Chemistry, 2024 - mdpi.com
In recent years, transdermal drug delivery systems have gained considerable attention for
their ability to enhance patient compliance and provide consistent drug release. However …

Transdermal application of diacerin loaded-terpene enriched invasomes: an approach to augment anti-edema and nociception inhibition activity

S Ahmed, MM Farag, MA Sadek… - Journal of Liposome …, 2024 - Taylor & Francis
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) to
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …

Inhibition of sympathetic activation by delivering calcium channel blockers from a 3D printed scaffold to promote bone defect repair

S Li, Z Li, J Yang, Y Ha, X Zhou… - Advanced Healthcare …, 2022 - Wiley Online Library
Enhancing osteogenesis by promoting neural network reconstruction and neuropeptide
release is considered to be an attractive strategy for repairing of critical size bone defects …

Integration of terpesomes loaded Levocetrizine dihydrochloride gel as a repurposed cure for Methicillin-Resistant Staphylococcus aureus (MRSA)-Induced skin …

MM El-Naggar, MA El-Nabarawi, MH Teaima… - International Journal of …, 2023 - Elsevier
The intention of this work is to assess the repurposed antimicrobial impact of Levocetirizine
dihydrochloride (LVC), which is a well-known antihistaminic drug, in addition, to augment …

Tailoring terpesomes and leciplex for the effective ocular conveyance of moxifloxacin hydrochloride (Comparative assessment): in-vitro, ex-vivo, and in-vivo evaluation

R Albash, MM Abdellatif, M Hassan… - International Journal of …, 2021 - Taylor & Francis
Aim To compare the ability of both terpesomes (TPs) and leciplex (LPs) loaded moxifloxacin
hydrochloride (MOX) for enhancing ocular drug conveyance. Methods Two separate 21.31 …

Low-frequency versus high-frequency ultrasound-mediated transdermal delivery of agomelatine-loaded invasomes: development, optimization and in-vivo …

MA Tawfik, MI Tadros, MI Mohamed… - International journal …, 2020 - Taylor & Francis
Aim Agomelatine (AGM) is the first melatonergic antidepressant. It suffers from low oral
bioavailability (< 5%) due to extensive hepatic metabolism. The current work aimed to …

Brain targeting of zolmitriptan via transdermal terpesomes: statistical optimization and in vivo biodistribution study by 99mTc radiolabeling technique

MA Tawfik, MM Eltaweel, AM Fatouh… - Drug Delivery and …, 2023 - Springer
Zolmitriptan (ZT) is a potent second generation triptan, commonly administered to alleviate
migraine attacks. ZT suffers various limitations; massive hepatic first pass metabolism, P-gp …

[HTML][HTML] pH-sensitive in situ gel of mirtazapine Invasomes for rectal drug delivery: Protruded bioavailability and anti-depressant efficacy

EM Eissa, AM El Sisi, MA Bekhet, FIA El-Ela… - Pharmaceuticals, 2024 - mdpi.com
The present research emphasizes fabrication alongside the assessment of an innovative
nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine …

Exploring the synergistic effect of bergamot essential oil with spironolactone loaded nano-phytosomes for treatment of acne vulgaris: In vitro optimization, in silico …

R Albash, NM Badawi, MIA Hamed, MH Ragaie… - Pharmaceuticals, 2023 - mdpi.com
The foremost target of the current work was to formulate and optimize a novel bergamot
essential oil (BEO) loaded nano-phytosomes (NPs) and then combine it with spironolactone …