Pharmaceutical cocrystals: An overview

N Qiao, M Li, W Schlindwein, N Malek, A Davies… - International journal of …, 2011 - Elsevier
Pharmaceutical cocrystals are emerging as a new class of solid drugs with improved
physicochemical properties, which has attracted increased interests from both industrial and …

[HTML][HTML] PDMAEMA based gene delivery materials

S Agarwal, Y Zhang, S Maji, A Greiner - Materials Today, 2012 - Elsevier
Gene transfection is the transfer of genetic material like DNA into cells. Cationic polymers
which form nanocomplexes with DNA, so-called non-viral gene vectors, are a highly …

Polylactide (PLA)-based amphiphilic block copolymers: synthesis, self-assembly, and biomedical applications

JK Oh - Soft Matter, 2011 - pubs.rsc.org
Polylactide (PLA) and its copolymers are one type of hydrophobic aliphatic polyester based
on hydroxyalkanoic acids. They possess exceptional qualities: biocompatibility; FDA …

Nanoformulations for combination or cascade anticancer therapy

L Miao, S Guo, CM Lin, Q Liu, L Huang - Advanced drug delivery reviews, 2017 - Elsevier
Nanoparticle drug formulations have been extensively investigated, developed, and in some
cases, approved by the Food and Drug Administration (FDA). Synergistic combinations of …

Stimuli-responsive tertiary amine methacrylate-based block copolymers: Synthesis, supramolecular self-assembly and functional applications

J Hu, G Zhang, Z Ge, S Liu - Progress in Polymer Science, 2014 - Elsevier
In the past decade, responsive polymers exhibiting reversible or irreversible changes in
physical properties and/or chemical structures in response to external stimuli have been …

Towards the development of polycaprolactone based amphiphilic block copolymers: molecular design, self-assembly and biomedical applications

Z Li, BH Tan - Materials Science and Engineering: C, 2014 - Elsevier
Polycaprolactone (PCL) and its copolymers are a type of hydrophobic aliphatic polyester
based on hydroxyalkanoic acids. They possess exceptional qualities: biocompatibility; FDA …

Supramolecular self-assembly forming a multifunctional synergistic system for targeted co-delivery of gene and drug

F Zhao, H Yin, J Li - Biomaterials, 2014 - Elsevier
For develo** a multifunctional bioreducible targeted and synergistic co-delivery system for
anticancer drug paclitaxel (PTX) and p53 gene for potential cancer therapy, supramolecular …

Polymeric co-delivery systems in cancer treatment: an overview on component drugs' dosage ratio effect

J Pan, K Rostamizadeh, N Filipczak, VP Torchilin - Molecules, 2019 - mdpi.com
Multiple factors are involved in the development of cancers and their effects on survival rate.
Many are related to chemo-resistance of tumor cells. Thus, treatment with a single …

[HTML][HTML] Dual responsive, stabilized nanoparticles for efficient in vivo plasmid delivery

H Wei, LR Volpatti, DL Sellers, DO Maris… - … (International ed. in …, 2013 - ncbi.nlm.nih.gov
Nucleic acid-based therapeutics, including plasmid DNA (pDNA) and small interfering RNA
(siRNA), have been considered highly promising strategies to treat a gamut of diseases.[1] …

Supramolecular anchoring of DNA polyplexes in cyclodextrin-based polypseudorotaxane hydrogels for sustained gene delivery

Z Li, H Yin, Z Zhang, KL Liu, J Li - Biomacromolecules, 2012 - ACS Publications
A cyclodextrin-based supramolecular hydrogel system with supramolecularly anchored
active cationic copolymer/plasmid DNA (pDNA) polyplexes was studied as a sustained gene …