CRISPR-related methods and compositions with governing gRNAS

F Zhang, D Palestrant, B Davidson, J Mata-Fink… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
51952032&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Cas9-recombinase fusion proteins and uses thereof

DR Liu, JP Guilinger, DB Thompson - US Patent 9,388,430, 2016 - Google Patents
2014-09-25 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Use of cationic lipids to deliver CAS9

DR Liu, JA Zuris, DB Thompson - US Patent 9,737,604, 2017 - Google Patents
2014-11-04 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Adenosine nucleobase editors and uses thereof

DR Liu, N Gaudelli - US Patent 10,113,163, 2018 - Google Patents
2018-08-06 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Delivery system for functional nucleases

DR Liu, JA Zuris, DB Thompson - US Patent 9,526,784, 2016 - Google Patents
2014-11-04 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Nucleobase editors and uses thereof

DR Liu, AC Komor, HA Rees, Y Kim - US Patent 10,167,457, 2019 - Google Patents
2017-04-10 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Methods for nucleic acid editing

DR Liu, AC Komor - US Patent 9,840,699, 2017 - Google Patents
US9840699B2 - Methods for nucleic acid editing - Google Patents US9840699B2 -
Methods for nucleic acid editing - Google Patents Methods for nucleic acid editing …

AAV delivery of nucleobase editors

DR Liu, JM Levy, WH Yeh - US Patent 11,306,324, 2022 - Google Patents
2018-02-22 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Cas variants for gene editing

DR Liu, AC Komor - US Patent 11,124,782, 2021 - Google Patents
2019-09-04 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Delivery system for functional nucleases

DR Liu, JA Zuris, DB Thompson - US Patent 10,682,410, 2020 - Google Patents
2016-06-22 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …