Tetrazole derivatives are a prime class of heterocycles, very important to medicinal
chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide …

Type-2 diabetes mellitus is one of the most prevalent metabolic diseases in the world, and is
characterized by hyperglycemia (ie, high levels of glucose in the blood). Alpha-glucosidases …

Abstract β-Mannans are plant cell wall polysaccharides that are commonly found in human
diets. However, a mechanistic understanding into the key populations that degrade this …

Substrate side chain conformation impacts reactivity during glycosylation and glycoside
hydrolysis and is restricted by many glycosidases and glycosyltransferases during catalysis …

β-Glucosidases (3.2. 1.21) are found in all domains of living organisms, where they play
essential roles in the removal of nonreducing terminal glucosyl residues from saccharides …

Abstract β-Glucosidases (3.2. 1.21) are found in all domains of living organisms, where they
play essential roles in the removal of nonreducing terminal glucosyl residues from …

Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal
storage disorder. Carriership for Gaucher disease has recently been identified as major risk …

High-value chemicals and energy-related products can be produced from biomass.
Biorefinery technology offers a sustainable and cost-effective method for this high-value …

Ginsenosides are the principal components responsible for the pharmaceutical activities of
ginseng. The minor ginsenosides, which are also pharmaceutically active, can be produced …

β-Glucosidases (EC 3.2. 1.21) cleave β-glucosidic linkages in disaccharide or glucose-
substituted molecules and play important roles in fundamental biological processes. β …