Lipocalin family proteins and their diverse roles in cardiovascular disease

HH Yang, X Wang, S Li, Y Liu, R Akbar… - Pharmacology & …, 2023‏ - Elsevier
The lipocalin (LCN) family members, a group of small extracellular proteins with 160-180
amino acids in length, can be detected in all kingdoms of life from bacteria to human beings …

Predictive and diagnostic biomarkers for gestational diabetes and its associated metabolic and cardiovascular diseases

A Lorenzo-Almorós, T Hang, C Peiró… - Cardiovascular …, 2019‏ - Springer
Gestational diabetes mellitus (GDM) is defined as the presence of high blood glucose levels
with the onset, or detected for the first time during pregnancy, as a result of increased insulin …

[HTML][HTML] Retinol, retinoic acid, and retinol-binding protein 4 are differentially associated with cardiovascular disease, type 2 diabetes, and obesity: an overview of …

T Olsen, R Blomhoff - Advances in Nutrition, 2020‏ - Elsevier
Vitamin A is a fat-soluble essential nutrient obtained from plant-and animal-based sources
that has roles in growth, vision, and metabolism. Vitamin A circulates mainly as retinol bound …

Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells

JM Yao, HZ Ying, HH Zhang, FS Qiu, JQ Wu… - Free Radical Biology and …, 2023‏ - Elsevier
Exosomes containing various biological cargoes have potential to be novel diagnostic
biomarkers for metabolic diseases. In this study, retinol-binding protein 4 (RBP4) was found …

Interplay of retinol binding protein 4 with obesity and associated chronic alterations

YA Flores-Cortez… - Molecular …, 2022‏ - spandidos-publications.com
Obesity is a multifactorial disease, defined as excessive fat deposition in adipose tissue.
Adipose tissue is responsible for the production and secretion of numerous adipokines that …

Bifidobacterium pseudocatenulatum CECT 7765 supplementation improves inflammatory status in insulin-resistant obese children

J Sanchis-Chordà, EMG Del Pulgar… - European journal of …, 2019‏ - Springer
Purpose The relationships between gut microbiota and obesity-related co-morbidities have
been increasingly recognized. Low-grade inflammation may be the main factor in the …

Serum biomarker panel for the diagnosis of rheumatoid arthritis

S Mun, J Lee, M Park, J Shin, MK Lim… - Arthritis research & …, 2021‏ - Springer
Background Rheumatoid arthritis (RA) is an autoimmune disease of inflammatory joint
damage, wherein C-reactive protein and autoantibodies including rheumatoid factor (RF) …

Retinol binding protein 4 and type 2 diabetes: from insulin resistance to pancreatic β-cell function

J Fan, J Hu - Endocrine, 2024‏ - Springer
Background and aim Retinol binding protein 4 (RBP4) is an adipokine that has been
explored as a key biomarker of type 2 diabetes mellitus (T2DM) in recent years …

Retinol and retinol binding protein 4 levels and cardiometabolic disease risk

C Schiborn, D Weber, T Grune, R Biemann… - Circulation …, 2022‏ - ahajournals.org
Background: Despite mechanistic studies linking retinol and RBP4 (retinol binding protein 4)
to the pathogenesis of cardiovascular diseases (CVD) and type 2 diabetes (T2D) …

Crosstalk between skin inflammation and adipose tissue-derived products: pathogenic evidence linking psoriasis to increased adiposity

A Chiricozzi, A Raimondo, S Lembo… - Expert Review of …, 2016‏ - Taylor & Francis
Introduction: Psoriasis is a chronic skin disorder associated with several comorbid
conditions. In psoriasis pathogenesis, the role of some cytokines, including TNF-α and IL-17 …