One of the hallmarks of cancer cells is their metabolic reprogramming, which includes the
preference for the use of anaerobic glycolysis to produce energy, even in presence of …

Cancer is a disease characterised by uncontrolled growth and proliferation of cells. Tumours
primarily show a higher rate of glucose uptake for lactate production even in the presence of …

Doxorubicin (DOX) is an extensively used chemotherapeutic drug to treat leukemia.
However, there remains a pivotal clinical problem of resistance to DOX in patients with …

To identify a novel amplified cancer gene a systematic screen of 975 human cancer DNA
samples, 750 cell lines and 225 primary tumors, using the Affymetrix 10K SNP microarray …

Aging is one of the major risk factors of cancer. The onset of cancer can be postponed by
pharmacological and dietary anti-aging interventions. We recently found in yeast cellular …

Multiple drug resistant (MDR) malignancy remains a predictable and often terminal event in
cancer therapy, and affects individuals with many cancer types, regardless of the stage at …

Aim: Metformin plays an important role in the inhibition of cancer cell growth and prolongs
remission durations. It reverses progestin‐resistance in endometrial cancer cells by …

Methyglyoxal (MGO), an essential endogenous dicarbonyl metabolite, can lead to multiple
physiological problems including hyperglycemia, kidney diseases, malignant tumors …

Objective No study has evaluated the antiproliferative effects of thiazolidinediones and
antiblastics in 'primary cultured human anaplastic thyroid cancer cells'. Design Primary …

Development of resistance in cancer cells results in a high failure rate in cancer
chemotherapy in the clinic. Therefore, investigating the mechanisms by which cancer cells …