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Digital labeling for 3D histology: segmenting blood vessels without a vascular contrast agent using deep learning
M Lapierre-Landry, Y Liu, M Bayat… - Biomedical Optics …, 2023 - opg.optica.org
Recent advances in optical tissue clearing and three-dimensional (3D) fluorescence
microscopy have enabled high resolution in situ imaging of intact tissues. Using simply …
microscopy have enabled high resolution in situ imaging of intact tissues. Using simply …
Nuclei detection for 3d microscopy with a fully convolutional regression network
M Lapierre-Landry, Z Liu, S Ling, M Bayat… - IEEE …, 2021 - ieeexplore.ieee.org
Advances in three-dimensional microscopy and tissue clearing are enabling whole-organ
imaging with single-cell resolution. Fast and reliable image processing tools are needed to …
imaging with single-cell resolution. Fast and reliable image processing tools are needed to …
CompassLSM: axially swept light-sheet microscopy made simple
Y Liu, AM Rollins, MW Jenkins - Biomedical optics express, 2021 - opg.optica.org
Axially swept light-sheet microscopy (ASLM) is an effective method of generating a uniform
light sheet across a large field of view (FOV). However, current ASLM designs are more …
light sheet across a large field of view (FOV). However, current ASLM designs are more …
A Simple and Fast Optical Clearing Method for Whole‐Mount Fluorescence In Situ Hybridization (FISH) Imaging
J Suh, Y Liu, J Smith, M Watanabe… - Journal of …, 2024 - Wiley Online Library
We report a single‐step optical clearing method that is compatible with RNA fluorescence in
situ hybridization (FISH) imaging. We previously demonstrated microscopy imaging with …
situ hybridization (FISH) imaging. We previously demonstrated microscopy imaging with …
Three-dimensional alignment of microvasculature and cardiomyocytes in the develo** ventricle
M Lapierre-Landry, H Kolesová, Y Liu, M Watanabe… - Scientific Reports, 2020 - nature.com
While major coronary artery development and pathologies affecting them have been
extensively studied, understanding the development and organization of the coronary …
extensively studied, understanding the development and organization of the coronary …
Digital Labeling of the Vasculature: Toward Label-Free and Labor-Free Vessel Segmentation
M Lapierre-Landry, Y Liu, M Bayat… - Bio-Optics: Design and …, 2023 - opg.optica.org
We propose digital labeling, a method for automated, three-dimensional segmentation of
blood vessels without vascular contrast agents. Our deep learning approach greatly …
blood vessels without vascular contrast agents. Our deep learning approach greatly …
Optical Image Analysis of Embryonic Heart Structure and Function
S Ling - 2022 - search.proquest.com
Congenital heart disease (CHD) is the most common birth defect and the leading cause of
infant death. The mechanisms behind CHD have been the focus of many studies but our …
infant death. The mechanisms behind CHD have been the focus of many studies but our …