The concept of 'successful aging'has long intrigued the scientific community. Despite this
long-standing interest, a consensus definition has proven to be a difficult task, due to the …

It has long been recognized that energy metabolism is linked to the production of reactive
oxygen species (ROS) and critical enzymes allied to metabolic pathways can be affected by …

Endoplasmic reticulum (ER) stress is transmitted to mitochondria and is associated with
pathologic mitochondrial dysfunction in diverse diseases. The PERK arm of the unfolded …

Cardiac tissue requires a persistent production of energy in order to exert its pum**
function. Therefore, the maintenance of this function relies on mitochondria that represent …

Abstract Hexavalent chromium (Cr (VI)), the most toxic valence state of chromium, is widely
present in industrial effluents and wastes. Although previous study has reported that Cr (VI) …

Abnormal function of suborganelles such as mitochondria and endoplasmic reticulum often
leads to abnormal function of cardiomyocytes or vascular endothelial cells and …

The endoplasmic reticulum (ER) and mitochondria form physical interactions involved in the
regulation of biologic functions including mitochondrial bioenergetics and apoptotic …

Introduction Muscle strength may play a role in cardiometabolic disease. We examined the
relationship between hand grip strength and diabetes and hypertension in a sample of …

The highly regulated processes of mitochondrial fusion (joining), fission (division) and
trafficking, collectively called mitochondrial dynamics, determine cell-type specific …

Evading apoptosis has been linked to tumor development and chemoresistance. One
mechanism for this evasion is the overexpression of prosurvival B-cell lymphoma-2 (BCL-2) …