Spirocyclic motifs are emerging privileged structures for drug discovery. They are also
omnipresent in the natural products domain. However, until today, no attempt to analyze the …

Over the years, alkaloids derived from indole dearomatization, such as indolenine and
indolines have been evolved as promising therapeutic agents due to their important …

Covering: 1986 to January 2011 Phytoalexins are antimicrobial secondary metabolites
produced de novo by plants in response to stress, including microbial attack. In general …

Drug-lead synthesis through rapid construction of chiral molecular complexity around the
biologically relevant framework using a highly efficient strategy is a key goal of organic …

Syntheses of organic compounds having a sulfur heteroatom have been in the interest of
many groups. This has been performed mainly through the reactions of thionating agents …

The glucosinolate pathway, which is present in the order Brassicales, is one of the most
researched defensive natural product biosynthesis pathways. Its core molecules, the …

Plants have developed effective defence strategies to protect themselves from
phytopathogenic microbes and herbivores in their environment. Disease resistance in plants …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit - Natural Product
Reports (RSC Publishing) DOI:10.1039/B820693G Royal Society of Chemistry View PDF …

A dearomative oxidation of pyrroles to Δ3‐pyrrol‐2‐ones is described, which employs a
sulfoxide as oxidant, in conjunction with a carboxylic acid anhydride and a Brønsted acid …

The indole nucleus is a prominent structural motif found in numerous natural products and
synthetic compounds with important biological activities, and thus considerable attention has …