The gut–liver axis and gut microbiota in health and liver disease

CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

Gut–liver axis: barriers and functional circuits

O Pabst, MW Hornef, FG Schaap, V Cerovic… - Nature Reviews …, 2023 - nature.com
The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …

Fecal microbiota transplantation compared with prednisolone in severe alcoholic hepatitis patients: a randomized trial

A Pande, S Sharma, V Khillan, A Rastogi, V Arora… - Hepatology …, 2023 - Springer
Background Severe alcoholic hepatitis (SAH) has high 90-day mortality. Prednisolone
therapy has shown modest survival benefits over placebo at 28 but not 90 days. Fecal …

Alcohol-associated liver disease—Global epidemiology

F Åberg, ZG Jiang, H Cortez-Pinto, V Männistö - Hepatology, 2024 - journals.lww.com
Alcohol-associated liver disease (ALD), as highlighted in this narrative review, is a major
public health concern, increasingly impacting global disease burden and premature …

Alcohol, the gut microbiome, and liver disease

MH Jew, CL Hsu - Journal of gastroenterology and hepatology, 2023 - Wiley Online Library
The microorganisms inhabiting our gastrointestinal tract are critical for human health.
Chronic heavy alcohol use can modulate the composition and function of the gut microbiota …

Gut-liver-brain axis and alcohol use disorder: treatment potential of fecal microbiota transplantation

JT Wolstenholme, NK Duong… - Alcohol Research …, 2024 - pmc.ncbi.nlm.nih.gov
PURPOSE Chronic alcohol use is a major cause of liver damage and death. In the United
States, multiple factors have led to low utilization of pharmacotherapy for alcohol use …

The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridioides difficile infection and other potential indications: of joint British Society of …

BH Mullish, B Merrick, MN Quraishi, A Bak… - Journal of Hospital …, 2024 - Elsevier
Summary The first British Society of Gastroenterology (BSG) and Healthcare Infection
Society (HIS)-endorsed faecal microbiota transplant (FMT) guidelines were published in …

Role of gut bacterial and non-bacterial microbiota in alcohol-associated liver disease: Molecular mechanisms, biomarkers, and therapeutic prospective

N Zafari, M Velayati, M Fahim, M Maftouh, G Pourali… - Life Sciences, 2022 - Elsevier
Alcohol-associated liver disease (ALD) comprises a spectrum of liver diseases that include:
steatosis to alcohol-associated hepatitis, cirrhosis, and ultimately hepatocellular carcinoma …

Gut-liver axis: Recent concepts in pathophysiology in alcohol-associated liver disease

FR Tonetti, A Eguileor, M Mrdjen, V Pathak… - Hepatology, 2024 - journals.lww.com
The growing recognition of the role of the gut microbiome's impact on alcohol-associated
diseases, especially in alcohol-associated liver disease, emphasizes the need to …

Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure

RK Jagdish, A Roy, K Kumar, M Premkumar… - Frontiers in …, 2023 - frontiersin.org
Cirrhosis transcends various progressive stages from compensation to decompensation
driven by the severity of portal hypertension. The downstream effect of increasing portal …