DePLM: Denoising Protein Language Models for Property Optimization

Z Wang, K Ding, M Qin, X Li… - Advances in …, 2025 - proceedings.neurips.cc
Protein optimization is a fundamental biological task aimed at enhancing theperformance of
proteins by modifying their sequences. Computational methodsprimarily rely on evolutionary …

Indole‐3‐Glycerol Phosphate Synthase From Mycobacterium tuberculosis: A Potential New Drug Target

N Esposito, DW Konas, NM Goodey - ChemBioChem, 2022 - Wiley Online Library
Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis, affects millions of
people worldwide. Several TB drugs have lost efficacy due to emerging drug resistance and …

Mise en évidence d'immunomodulations médiées par les métabolites: de l'identification à l'application en contexte infectieux

C Plazy - 2022 - theses.hal.science
En contexte d'infection chronique, les bactéries vont s' adapter à l'environnement
pulmonaire du patient et à la pression exercée par le système immunitaire en sécrétant ou …

A multi-omic analysis of the role of aminolipids under nutrient limitation and phage infection in Ruegeria pomeroyi DSS-3

R Stirrup - 2022 - wrap.warwick.ac.uk
Marine microbes adapt to changing conditions in the oceans in a variety of ways. A common
strategy includes substituting membrane phospholipids for non-P-containing lipids. Amino …