Background Numerous clinical trials and observational studies have investigated various
pharmacological agents as potential treatment for Coronavirus Disease 2019 (COVID-19) …

Network meta‐analysis (NMA) is an extension of pairwise meta‐analysis (PMA) which
combines evidence from trials on multiple treatments in connected networks. NMA delivers …

Objective Meta-analyses of observational studies are frequently published in the literature,
but they are generally considered suboptimal to those involving randomised controlled trials …

Objectives Compare the safety of antiepileptic drugs (AEDs) on neurodevelopment of
infants/children exposed in utero or during breast feeding. Design and setting Systematic …

Organisations such as the National Institute for Health and Care Excellence require the
synthesis of evidence from existing studies to inform their decisions—for example, about the …

Importance A substantial increase in the number of trials examining metacognitive training
(MCT) for psychosis necessitates an updated examination of the outcomes associated with …

Background The trade-off between comparative effectiveness and reproductive morbidity of
different treatment methods for cervical intraepithelial neoplasia (CIN) remains unclear. We …

Healthcare decisions should be based on all relevant evidence. 1 Usually, this is provided
by randomised controlled trials (RCTs) comparing two or more interventions for a condition …

The aim of this systematic review and network meta‐analysis is to evaluate the comparative
effectiveness of N95, surgical/medical and non‐medical facemasks as personal protective …

Building trust in science and evidence-based decision-making depends heavily on the
credibility of studies and their findings. Researchers employ many different study designs …