Asymmetric organocatalytic oxidations have been witnessed to an impressive development
in the last years thanks to the establishment of important chiral hypervalent iodines (III/V) …

Isocoumarins are lactonic natural products abundant in microbes and higher plants. These
are considered an amazing scaffold consecrated with more or less all types of …

Ongoing efforts have been dedicated to the development of reaction processes controlled by
chiral hypervalent iodine reagents with high enantioselectivity.[1–12] The oxidation of …

A facile and enantioselective approach toward 3, 4-dihydroisocoumarin was developed. The
method involved an amino-thiocarbamate catalyzed enantioselective bromocyclization of …

Abstract Mammalian cytochrome P450 1A (CYP1A) are key phase I xenobiotic‐metabolizing
enzymes that play a distinctive role in metabolic activation or metabolic clearance of a …

Human health is beset with a legion of ailments, which is exacerbated by lifestyle errors. Out
of the numerous enzymes in human body, aromatase, a cytochrome P450 enzyme is …

As one of the main extra‐hepatic cytochrome P450 (CYP) enzymes, CYP1A1 has been
comprehensively investigated for its ability to metabolize both exogenous and endogenous …

MaZiRenWan (MZRW, also known as Hemp Seed Pill) is a Chinese Herbal Medicine which
has been demonstrated to safely and effectively alleviate functional constipation (FC) in a …

Although a wide variety of chiral organocatalysts have been developed for asymmetric
transformations, effective chiral dialkyl sulfide organocatalysts remain relatively rare and …

Aromatase (CYP19) catalyzes the aromatization reaction of androgen substrates to
estrogens, the last and rate-limiting step in estrogen biosynthesis. Inhibition of aromatase is …