IgG4-related disease: an update on pathophysiology and implications for clinical care

CA Perugino, JH Stone - Nature Reviews Rheumatology, 2020 - nature.com
Abstract IgG4-related disease (IgG4-RD) has only existed as a unique disease entity since
2003, yet remarkable progress has already been achieved in describing the essential …

Advances in the diagnosis and management of IgG4 related disease

M Lanzillotta, G Mancuso, E Della-Torre - Bmj, 2020 - bmj.com
IgG4 related disease was recognized as a unified disease entity only 15 years ago.
Awareness of IgG4 related disease has increased worldwide since then, and specialists are …

[HTML][HTML] Intratumoral CD4+ T cells mediate anti-tumor cytotoxicity in human bladder cancer

DY Oh, SS Kwek, SS Raju, T Li, E McCarthy, E Chow… - Cell, 2020 - cell.com
Responses to anti-PD-1 immunotherapy occur but are infrequent in bladder cancer. The
specific T cells that mediate tumor rejection are unknown. T cells from human bladder …

IgG4-related diseases of the digestive tract

JM Löhr, M Vujasinovic, J Rosendahl… - Nature Reviews …, 2022 - nature.com
IgG4-related conditions affecting the digestive tract are part of a multi-organ fibro-
inflammatory disorder termed IgG4-related disease (IgG4-RD), with autoimmune pancreatitis …

Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis

T Maehara, N Kaneko, CA Perugino… - The Journal of …, 2020 - Am Soc Clin Investig
Systemic sclerosis (SSc) is an autoimmune fibrotic disease whose pathogenesis is poorly
understood and lacks effective therapies. We undertook quantitative analyses of T cell …

IgG4-related disease: a clinical perspective

F Maritati, F Peyronel, A Vaglio - Rheumatology, 2020 - academic.oup.com
Abstract IgG4-related disease (IgG4-RD) is a recently recognized fibro-inflammatory
disorder that can affect almost any organ. Common presentations include major salivary and …

Management of IgG4-related disease

W Zhang, JH Stone - The Lancet Rheumatology, 2019 - thelancet.com
IgG4-related disease was unrecognised as a unified disease entity until this century, yet in a
short period of time the disease has been appreciated to have a worldwide distribution, and …

Clinical perspectives on IgG4-related disease and its classification

G Katz, JH Stone - Annual review of medicine, 2022 - annualreviews.org
Immunoglobulin G4–related disease (IgG4-RD) is a systemic immune-mediated
fibroinflammatory disease. Since its discovery nearly two decades ago, our understanding of …

Long-term efficacy and safety of rituximab in IgG4-related disease: data from a French nationwide study of thirty-three patients

M Ebbo, A Grados, M Samson, M Groh, A Loundou… - PLoS …, 2017 - journals.plos.org
Objectives To assess efficacy and safety of rituximab (RTX) as induction therapy,
maintenance of remission and treatment of relapses in a cohort of IgG4-related disease …

Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren's Syndrome

X Hong, S Meng, D Tang, T Wang, L Ding… - Frontiers in …, 2021 - frontiersin.org
Objective Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease, and its
pathogenetic mechanism is far from being understood. In this study, we aimed to explore the …