Simple Summary Over the past two decades, biological discoveries have transformed the
treatment strategies for renal cell carcinoma. These advances have led to the development …

Oligometastatic renal cell carcinoma (OM-RCC) refers to patients who have limited (typically
up to 5) metastatic lesions. Although management principles may overlap, OM-RCC is …

In the United States, an estimated 79,000 cases and 13,920 deaths will be attributable to
kidney cancer in 2022. 1 Most kidney cancers are primary renal cell carcinomas (RCC) of …

Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor
survival and a heightened response to immune checkpoint inhibitors (ICIs). Two major …

A man aged 41 years who had a past medical history significant for bilateral lower extremity
varicosities and a prior 20‐pack‐year smoking history reported several days of fatigue to his …

Background This pooled analysis of patient-level data from trials evaluated the clinical
outcomes of patients with metastatic renal cell carcinoma with or without cytoreductive …

In the past decades, several treatments have been proposed for the management of
metastatic renal cell carcinoma (mRCC). Among these, cytoreductive nephrectomy (CN) …

Cytoreductive nephrectomy became accepted as standard of care for selected patients with
metastatic renal cell carcinoma (mRCC) because of improved survival observed in patients …

Background The role of cytoreductive nephrectomy (CN) has not yet been well characterized
in the era of combination immunotherapy. Objective To evaluate characteristics and …

Background About 20% of patients with renal cell carcinoma present with non-clear cell
histology (nccRCC), encompassing various histological types. While surgery remains pivotal …