Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions

X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

2‐Iodoxybenzoic acid—a simple oxidant with a dazzling array of potential applications

A Duschek, SF Kirsch - Angewandte Chemie International …, 2011 - Wiley Online Library
Since its discovery by Christoph Hartmann and Victor Meyer in 1893, 2‐iodoxybenzoic acid
(IBX) has emerged as a rather ubiquitous oxidant for organic synthesis. The past decade …

One‐Pot, Direct Incorporation of [11C]CO2 into Carbamates

JM Hooker, AT Reibel, SM Hill… - Angewandte Chemie …, 2009 - Wiley Online Library
Why beat about the bush? An operationally simple and mild reaction based on the direct
fixation of 11CO2 with 1, 8‐diazabicyclo [5.4. 0] undec‐7‐ene (DBU) has been developed …

[HTML][HTML] Cu (I)-catalyzed 11C-carboxylation of boronic acid esters: a rapid and convenient entry to 11C-labeled carboxylic acids, esters and amides

PJ Riss, S Lu, S Telu, FI Aigbirhio… - … Chemie (International ed …, 2012 - ncbi.nlm.nih.gov
Non-invasive imaging with positron emission tomography (PET) allows for quantitative
studies of radiotracer distribution in living subjects and is increasingly used in routine clinical …

11C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α‐Synuclein Fibrils in vitro and Crosses the Blood‐Brain Barrier

A Maurer, A Leonov, S Ryazanov, K Herfert… - …, 2020 - Wiley Online Library
There is an urgent clinical need for imaging of α‐synuclein (αSyn) fibrils, the hallmark
biomarker for Parkinson's disease, in neurodegenerative disorders. Despite immense …

[PDF][PDF] Methods for the Incorporation of Carbon-11 To Generate Radiopharmaceuticals for PET Imaging PET= positron emission tomography.

PJH Scott - 2009 - deepblue.lib.umich.edu
Positron emission tomography (PET) imaging is an exciting and rapidly growing area of
research in which short-lived radionuclides, such as carbon-11 and fluorine-18, are …

Direct [11C]Methylation of Amines from [11C]CO2 for the Synthesis of PET Radiotracers

F Liger, T Eijsbouts, F Cadarossanesaib… - European Journal of …, 2015 - Wiley Online Library
Abstract [11C] Methylation (t1/2= 20.4 min) is a main labeling strategy for the development of
PET (positron emission tomography) radiotracers. A straight radiomethylation of amines with …

Carbon‐11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget

T Haywood, S Kealey… - … A European Journal, 2015 - Wiley Online Library
Herein a new 11C radiolabelling strategy for the fast and efficient synthesis of thioureas and
related derivatives using the novel synthon, 11CS2, is reported. This approach has enabled …

11C‐Labeling: Intracyclic Incorporation of Carbon‐11 into Heterocycles

F Liger, F Cadarossanesaib, T Iecker… - European Journal of …, 2019 - Wiley Online Library
Labeling of heterocycles with carbon‐11 is generally performed through peripheral
functionalizations and more scarcely inside heterocyclic core. Such less common approach …